Metalurji ve Malzeme Mühendisliği Bölümü Kitap Koleksiyonu

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https://hdl.handle.net/20.500.12418/636

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Biocomposites: Advances in Research and Applications Chapter 6. Dental Bioceramics: From Lab to Clinical Practice
(Nova Science Publishers, Inc., November 13, 2023) Öksüz, Kerim Emre
Functional ceramics known as bioceramics have gained significant interest in the field of regenerative medicine. They have been widely used as bone reconstructive materials in orthopedics, oral and maxillofacial surgery. One of the most commonly used materials in clinical applications are those based on calcium phosphate (Ca3(PO4)2) and calcium silicate (Ca2SiO4), which have been available on the market for several decades. Currently, there are ongoing works to develop bioceramics for various clinical applications in regenerative medicine, including dentistry. Bioceramics have shown promise in periodontal treatment, prevention of relapse, nerve regeneration, drug delivery technology, and even in esthetic medicine and cosmetics. For restorations in the anterior of the mouth, glass ceramics are an alternative approach to provide both esthetics and strength, while (Al2O3) alumina and (ZrO2) zirconia-based structural ceramics are utilized as crown cores and bridge frameworks. However, they require the application of an esthetic veneering ceramic for clinical use in tooth structure replacement. This chapter discusses the advantages of dental bioceramics, their compositions, biological evolutions, and how their physical properties relate to clinical findings. The future perspective and challenges in using bioceramics for next-generation regenerative therapy are also discussed.
ULTRASONİK NANOKRİSTAL YÜZEY MODİFİKASYONU (UNYM) YÖNTEMİ VE GÜNCEL GELİŞMELER
(2023) Selçuk, Erhan; Şimşir, Mehmet
UNYM, patentli bir teknolojidir. Design Mecha Co., Ltd tarafından geliştirilmiş ve ticarileştirilmiştir (Amanov, Cho, Pyoun, vd., 2012). UNYM, son zamanlarda geliştirilmiş mekanik aşırı yüzey plastik deformasyonu teknolojisidir. Malzeme yüzeyinde aşırı plastik deformasyon oluşturmak için statik yüke ek olarak yüzey nanokristalleşmesini sağlayan düşük frekanslı ultrasonik titreşimi kullanır. Mekanik darbelerle malzeme yüzeyinde plastik deformasyon başlatılır. Ucun yüksek frekanslı darbesi, malzeme yüzeyi üzerinde yüksek yoğunlukta dislokasyon ve tane sınırlarının oluşmasını sağlayan aşırı plastik deformasyona neden olur. Darbe sayısı arttıkça, yüzeydeki basma kalıntı gerilmesi de artar. Bunun sonucu olarak malzemenin yorulma direnci de artar. Dolayısıyla, şokların sayısı arttıkça malzeme yüzeyindeki nanokristal yüzey tabakası oluşumunun kalınlığı da artmaktadır. Tungsten karbür ucun titreşimli hareketi sayesinde yüzeyde oluşan çukurlar, yüzeyde parlatma etkisi yaparak yüzey profilini düzleştirir (Syed & Sundaram, 2023). Endüstriyel uygulama alanlarında çok yüksek mukavemet, yorulma ömrü, aşınma direnci ve korozyon direncinin gerekli olduğu: Havacılık (Nascimento vd., 2001), gemi ve denizcilik (Kirkhope vd., 1999; Deguchi vd., 2012) otomotiv (Kudryavtsev & Kleiman, 2005), demiryolu (Zou vd., 2021) ve köprü yapıları (Yin vd., 2010) gibi alanlarda kullanılmaktadır. Şekil 1’de UNYM cihazının çalışma prensibi sunulmuştur.
ANTIBACTERIAL NATURAL DYES AND APPLICATIONS
(2023) Kayaş, Esra; Canpolat, Rahmi; Özaydın, Fatih; Şimşir, Mehmet
Since natural dyes have therapeutic properties in the literature, these dyes have created awareness and the demand for these dyes has increased considerably. Natural dyes are obtained from naturally occurring sources. Among all natural dyes, dyes composed of pigments of plants have extensive medicinal value. The dyestuffs of natural dyes and the medicinal properties of these substances have been known for many years, but their structures and protective properties have only been understood recently. Many of the plants used for dye extraction are classified as medicinal, and some of these have recently been shown to have remarkable antimicrobial activity. New research reveals detailed information about the basic chemistry of the main pigments found in naturally occurring dye-yielding plants and their medical significance, which helps in the further development of pharmaceutical formulations (Chengaiah et al, 2010).
PARAMETERS AFFECTING MICRO ARC OXIDATION PROCESS, BIOCOMPATIBILITY AND PARTICLE ADDITION
(2023) Ünlüses, Kadir; Şimşir, Mehmet; Yabaş, Ebru
Micro Arc Oxidation (MAO) is used in many areas in the biomedical applications (medicine, dentistry), automotive, military, textile industry, maritime industry, aircraft and space sectors because it creates high temperature resistant coatings and shows high di-electric properties. Due to this feature, it is especially important in the space industry in the production of protective coatings of missiles and space shuttles. In addition, MAO technology is used in chemical applications because it is resistant not only to high temperatures but also to medium temperatures and strong acids and bases; In mechanical applications as a factor that increases wear resistance due to its high oxide hardness (> 1300 kg/mm2) layer; It is a surface modification process that can be used in thermal and electrical-electronic applications (Sun et al., 2005, Günyüz, 2007, Mostofizadeh et al., 2011) Compared to anodic oxidation, MAO technology is superior with its higher coating formation rate and thickness due to the ability to reach higher voltages. MAO technology is a superior process to the plasma spraying method with its high adhesion force that develops with the substrate material. When compared to the hard chrome plating method in terms of the electrolytes used, it is seen that the alkaline electrolytes used in the MAO process are not harmful to the environment. In short, the MAO process is seen as a technology that continues to develop, provides high tribological properties, and will replace many of the traditional coatings with its advanced surface treatment method (Lee et al., 2008, Morks et al., 2011, Malayoglu et al., 2011). An ideal metallic biomaterial used in dentistry and orthopedic fields; It is required to have biocompatibility, relatively low density, contain little or no toxic metals in its structure, have high strength and long fatigue life, low elastic modulus (compared to cortical bone), plasticity at wide ambient temperatures and be perfect. Titanium and its alloys are shiny and have a high specific strength (strength/density) ratio. Titanium and its alloys are widely used in dental and orthopedic applications due to their excellent biocompatibility, mechanical properties, excellent corrosion resistance and ease of machinability (Rautray et al., 2011). Biocompatibility is the ability of a material to perform its function in the presence of the appropriate environment for a specific application. The materials used as implants are expected to be highly non-toxic and should not cause any inflammation or 105 | Current Research From Science to Technology allergic reactions in the human body (Geetha et al., 2009). The success of biomaterials depends mainly on the reaction of the living body towards the implant material. Due to the presence of a passive and stable thin oxide film (TiO2) formed on the surface of titanium, it is relatively inert, has high corrosion resistance and superior biocompatibility. Since the oxide layer on the titanium surface is homogeneous and dense, the titanium implant does not interact with tissues and also regenerates immediately if the passive layer is damaged (Liu, et al., 2004). The surfaces of titanium and its alloys play an important role in implant integration in the living body. As a result of different surface modifications, the properties specified in the following items can be achieved. •Better mechanical fixation of the implant to the bone tissue (improvement of bone bonding with the implant) •Improvement of bone permeability and inductivity •Improving wear resistance •Improving corrosion resistance •Improvement of biocompatibility and bioactivity •Shortening recovery time after implantation In this article, the parameters of the micro arc oxidation process and biocompatibility are examined.
Biocomposites: Advances in Research and Applications Chapter 2. Boron-Substituted Biomaterials
(Nova Science Publishers, Inc., November 13, 2023) Nader, Abuhamed; Arslan, Saynur; Öksüz, Kerim Emre
Biomaterial scientists are interested in boron as a dopant element because of its natural functions in human hard tissues. However, boron does not exist in its elemental form in nature. Instead, it reacts with oxygen to form boric acid (H3BO3). Boron occurs naturally as borates, including orthoborate.
CHARACTERIZATION TECHNIQUES OF HERBAL ESSENTIAL OILS
(2022) Ebru YABAŞ; Fuat Erden; Mehmet Şimşir
In the characterization of essential oils, techniques such as Fourier- Transform Infrared Spectroscopy, Raman Spectroscopy, Gas Chromatography-Mass Spectrometry, Differential Scanning Calorimetry, Nuclear Magnetic Resonance Spectrometer are generally used. In this part of the chapter, information about these techniques is separately given.

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