The Different Effects of Metal Ions on the Synthesis of Macroacyclic Compounds: X-ray Crystal Structure, Theoretical Studies, Antibacterial and Antifungal Activities
Küçük Resim Yok
Tarih
2019
Yazarlar
Rezaeiyala, M.
Golbedaghi, R.
Khalili, M.
Ahmad, M.
Sayin, K.
Chalabian, F.
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
PLEIADES PUBLISHING INC
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this work, we have been involved studying the synthesis of some new macroacyclic complexesI-VIII, so we tried to get propoesed results in all cases but in the case of compound I, according to X-ray crystal structure, the product is a protonated Schiff base. By the reaction of a 1 : 1 (metal : ligand) stoichiometry of two known Schiff base ligands, 1,2-bis(2-((2-hydroxy ethylimino)methyl)phenoxy)ethane (H2L1) or 1,3-bis(2-((2-hydroxyethylimino)methyl) phenoxy)propane (H2L2) and appropriate metal salts in methanol in the case of Ni2+, Cu2+ and Co2+, macroacyclic complexes were prepared. When using Mn2+ only protonated Schiff base ligands is the final product. All compounds were characterized by microanalysis and IR spectroscopy, whereas compound I was also characterized by single crystal X-ray. The X-ray structure of compound I showed that both protonated imines are neutralized by two perchlorate ions. Computational calculations of relevant complexes are done by using one of the hybrid density functional theories which are a B3LYP method with 6-31G(d) basis set in a vacuum. Also, the synthesized compounds were screened for their antibacterial activities against nine bacterial strains and showed antibacterial effects. These complexes also showed antifungal effects on two species of Candida.
Açıklama
Anahtar Kelimeler
Schiff base ligands, the effect of metal ions, protonated imine, antibacterial, antifungal, crystal structure, theoretical studies
Kaynak
RUSSIAN JOURNAL OF COORDINATION CHEMISTRY
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
45
Sayı
2
