Sahin, NeslihanDusunceli, Serpil DemirOzdemir, Ismail2019-07-272019-07-282019-07-272019-07-2820170385-54141881-0942https://dx.doi.org/10.3987/COM-17-13737https://hdl.handle.net/20.500.12418/6715Aminoarenes constitute valuable building blocks in organic synthesis and an essential skeleton ubiquitously found in ligands, agrochemicals, and pharmaceuticals. This synopsis presents recent amination methods using nitrogen-heteroatom bonds as a powerful and versatile platform to rapidly synthesize diverse aminoarenes, with transition-metal catalyzed arene C-H amination. The Buchwald-Hartwig amination has been investigated theoretically and experimentally to examine the scope of possible bases under different reaction conditions. We report examples of the palladium NHC (N-heterocyclic carbene) catalyzed amination of aryl halides with anilines and amines in the presence of dimethoxyethane solvent and potassium tertiary-butoxide as a base.en10.3987/COM-17-13737info:eu-repo/semantics/closedAccessArticle948151715062-s2.0-85026304095Q4WOS:000408301300006Q4