Tugut, FaikKoyu, TugceTurkyilmaz, Orhun2025-05-042025-05-0420242320-20682320-2076https://doi.org/10.1177/23202068241269854https://hdl.handle.net/20.500.12418/35319Aim: This study set out to determine the tensile bond strength between denture bases (produced by 3D printing technology, conventional technique, and computer-aided design and computer-aided manufacturing [CAD/CAM] milled) and silicone-based soft lining material. The consequence of thermocycling on the bonding strength was also investigated. Materials and Methods: The bonding between denture foundation materials produced through three distinct techniques (conventional, CAD/CAM milled, and 3D printed) and silicone-based soft lining material was examined. Before tensile testing, half of the samples underwent thermocycling (5-55 degrees C, 5,000 cycles) in 37 degrees C distilled water for 48 hours. A universal testing apparatus employed a crosshead speed of 5 mm/min. The failure type was identified visually, and the maximum tensile strength was noted. The Shapiro-Wilk test and analysis of variances (P = .05) were used to assess the statistics. Results: CAD/CAM milled denture base material (1.56 +/- 0.62/1.36 +/- 0.16 MPa) showed higher bond strength values than the other denture bases in the tensile test conducted before and after thermocycling (P < .001). The denture base material made conventionally had the lowest bond strength (1.02 +/- 0.24/0.77 +/- 0.1 MPa) (P < .001). The tensile bond strength values of the conventional and 3D printing groups showed a statistically significant drop before and after thermocycling (P = .001). Regardless of thermocycling, adhesive failure was primarily seen in all groups (76.6%). Conclusion: Compared to conventionally produced denture bases, the bond strength of soft relining materials to CAD/CAM milled and 3D printed denture base is different. In denture base materials that are conventionally, CAD/CAM and 3D printed, the thermocycling method reduced bonding strength values.en10.1177/23202068241269854info:eu-repo/semantics/closedAccessCAD/CAM3D printingSoft denture linerPolymethylmethacrylateArticle1521301242-s2.0-85207312256Q3WOS:001335687600006N/A