Çağlayan, İlkin Seda CanKılıç, Vildan2025-05-042025-05-0420241305-3124https://doi.org/10.59215/prn.24.0322010https://hdl.handle.net/20.500.12418/34971Objective: The aim of our study was to detect an increase in nuchal translucency (NT) measurement among our patients attending our clinic for 11-14 weeks of control and to examine the perinatal and postnatal outcomes of pregnant women who were recommended an invasive fetal procedure but refused it. Methods: 107 pregnant women between 11-14 weeks of gestation who were evaluated in our center from 2018 to 2021 and who rejected invasive procedures were included. Patients opting for follow-up and delivery at another facility were excluded from the study. The study groups were categorized into 3 groups based on NT values, regardless of gestational age: 1st Group 2.5-3.4 mm, 2nd Group 3.5-4.5 mm, and 3rd Group>4.5 mm. Fetal ultrasound scans were conducted during the antenatal period, with detailed examinations postnatally. Results: Abnormal ultrasound findings were detected in 11.2% of fetuses, with a higher prevalence in groups exhibiting greater NT increases. While chromosomal anomaly was seen in 13% of all fetuses, Group 2 (NT 3.5-4.5mm) had the highest percentage (33.3%). The highest right and healthy birth rates were found in group 1 (91.8%), inversely proportional to the increase in NT. Conclusion: Increased NT values appear to be associated with increased rates of structural anomalies and adverse perinatal outcomes. Although chromosomal anomalies are associated with NT increase, a direct proportional relationship between the two remains undetermined. © 2024 Perinatal Medicine Foundation.en10.59215/prn.24.0322010info:eu-repo/semantics/closedAccessdecision-makingFirst trimesternuchal translucencyperinatal outcomeprenatal testingArticle3221601552-s2.0-85206801376Q4