Ozturk, HayatiBulut, OkayOztemur, ZekeriyaKaloglu, CelalKol, Iclal Ozdemir2019-07-272019-07-282019-07-272019-07-2820080936-80511434-3916https://dx.doi.org/10.1007/s00402-007-0388-6https://hdl.handle.net/20.500.12418/10361Introduction We investigated the effect of high-energy extracorporeal shock wave (ESW) on immature tibial epiphysis in a rabbit model. Materials and methods Twenty New Zealand white immature rabbit were used in this study. Animals were divided into two groups and they received 14 kW, 0.6 mJ/mm(2), 1,500 or 3,000 shots for three times with an interval of 7 days. After 6 weeks all rabbits were killed. The all tibia epiphysis were assessed by histology. The epiphyseal plaque thickness of right tibiae of the 3,000-shot ESW group was significantly higher than those of the 1,500-shot ESW group and the left tibia epiphyses of the 1,500- and 3,000-shot ESW groups as controls (P < 0.05). Results The epiphyseal plaque thickness of right tibiae of the 1,500-shot ESW group was significantly higher than that of the left tibia epiphyses of the 1,500- and 3,000-shot ESW groups as controls (P < 0.05). Discussion We demonstrated that high-energy ESW stimulated the growth of immature rabbit epiphysis. The long-term effect of shock wave on the immature rabbit epiphysis deserves further study.en10.1007/s00402-007-0388-6info:eu-repo/semantics/closedAccessepiphysisextracorporeal shock wave (ESW)high energyrabbitArticle1286631627176245372-s2.0-42549122980Q1WOS:000255189700015Q3