Karadag, AhmetDogan, Halef Okan2024-10-262024-10-2620212147-2653https://doi.org/10.4274/tod.galenos.2021.45403https://search.trdizin.gov.tr/tr/yayin/detay/527464https://hdl.handle.net/20.500.12418/27722Objective: This study aimed to investigate the serum levels of calprotectin, hepcidin, iron, and ferritin in Behcet's disease (BD). Materials and Methods: This study included 40 patients with BD who met the diagnostic criteria of the BD International Study Group (1990) and 40 healthy control participants. Serum high-sensitive C-reactive protein (hsCRP), hepcidin, calprotectin, ferritin, iron, and unsaturated iron-binding capacity (UIBC) levels were determined in all study participants. Results: Statistically significant difference was found between the groups in respect of calprotectin (p<0.05), UIBC (p<0.05), hsCRP (p<0.05), and hemoglobin (p<0.05) levels. No statistically significant differences were determined between the patients and the controls in terms of hepcidin, iron, and ferritin levels. Cut-off value of 212.3 pg/mL for calprotectin was determined to identify patients with BD having a sensitivity and specificity of 100% and 90%, respectively. Conclusion: Serum calprotectin may be a useful biomarker in the evaluation of inflammatory status and BD diagnosis. Total iron-binding capacity and hemoglobin may be more useful in evaluating iron deficiency anemia in patients with BD.en10.4274/tod.galenos.2021.45403info:eu-repo/semantics/openAccessBehcet's diseasecalprotectinhepcidinironferritinReview Article2731441402-s2.0-85123835633Q4527464WOS:000753766500003N/A