Tutar, LutfiTutar, Yusuf2019-07-272019-07-282019-07-272019-07-2820080006-3525https://dx.doi.org/10.1002/bip.20881https://hdl.handle.net/20.500.12418/10415Yeast cytosol has two important co-chaperons; Ydj1 and Sis1. Genetic experiments showed that Ydj1 is not I essential for viability; however, cells lacking it grow very poorly at 30 degrees C or unable to grow at extreme temperatures. On the other hand, Sis1 is an essential protein and apparently plays a functional role at assembly or disassembly of protein complexes. Stability experiments revealed that only Ydj1-protected Hsp70 proteins can hydrolyze ATP under prolonged stress. (c) 2007 Wiley Periodicals, Inc.en10.1002/bip.20881info:eu-repo/semantics/closedAccessstabilityHsp70Ydj1Sis1Ydj1 but not Sis1 stabilizes Hsp70 protein under prolonged stress in vitroArticle893174171179853672-s2.0-38949188609Q2WOS:000253245900001Q2