Cakmak, Nese KeklikciogluTezel, Guler Bengusu2024-10-262024-10-2620191583-3186https://hdl.handle.net/20.500.12418/29339In this study, graphene oxide nanoparticle (NGO) was fabricated via modified Hummers' method and then modified with amine terminated 4-armed PEG to enhance the biocompatibility and stability of nano drug carrier. In our strategy, Doxorubicin (DOX) was used as a model drug. DOX loading onto NGO-PEG was synthesized by simply mixing with the NGO-PEG solution at pH 7 overnight. NGO, NGO-PEG and NGO-PEG-DOX was characterized by power X-ray diffraction, scanning electron microscopy, and UV spectroscopy. Stability analysis was performed with zeta potential. The experimental results showed that the zeta potential analysis values were above +/- 40 mV. NGO-PEG-DOX is still had very good dispersion stability even after 45 days. Therefore, this drug loaded product can be good candidate for treatment of cancer.eninfo:eu-repo/semantics/closedAccessnanographene oxide (NGO)nanostructured drug carrierstabilityDOXPEGylatedArticle493351346WOS:000487262400005Q4