Nemati, MahboobAltunay, NailTuzen, MustafaFarajzadeh, Mir AliAfshar Mogaddam, Mohammad Reza2024-10-262024-10-2620221615-93061615-9314https://doi.org/10.1002/jssc.202100963https://hdl.handle.net/20.500.12418/30534An organic polymer was re-precipitated in solution to use as an adsorbent in dispersive solid-phase extraction of some pesticides from honey samples prior to their determination by high-performance liquid chromatography-tandem mass spectrometry. In this approach, different deep eutectic solvents were prepared using lysine and their ability in elution of the analytes from the adsorbent surface was tested. A diluted honey solution was transferred into a glass test tube and then a solution of polystyrene dissolved in dimethylformamide was injected into the solution. By doing this, polystyrene is re-precipitated in the solution and dispersed in whole parts of it as many tiny particles. Then the mixture was centrifuged and the adsorbed analytes on the particles were eluted using a proper hydrophilic deep eutectic solvent. The central composite design approach was used for the optimization of effective parameters. The limits of detection and quantification were in the ranges of 0.06-0.20 and 0.22-0.69 ng/g, respectively. The calibration curves obtained by matrix-matched standard solutions were linear in the range of 0.69-500 ng/g with a coefficient of determinations >= 0.9962. The method provided high extraction recoveries (70%-99%) and enrichment factors (140-198), and an acceptable precision (relative standard deviations <= 7.1%).en10.1002/jssc.202100963info:eu-repo/semantics/closedAccessdispersive solid-phase extractionexperimental designhigh-performance liquid chromatographyhoneypesticidetandem mass spectrometryArticle451426622652355965222-s2.0-85131016686Q2WOS:000803753700001Q2