Ozum, UnalEgilmez, ReynahYildirim, Altan2019-07-272019-07-282019-07-272019-07-2820080919-6544https://dx.doi.org/10.1111/j.1440-1789.2008.00885.xhttps://hdl.handle.net/20.500.12418/10305Paragangliomas are neuroendocrine tumors of paraganglionic tissue which are extremely rare in the sellar area. We present a case of sellar paraganglioma with parasellar and suprasellar extension in a 70-year-old man who presented with headache. CT demonstrated sellar mass with suprasellar and right parasellar extension. The lesion was removed subtotally via a trans-sphenoidal approach. Histopathological diagnosis was paraganglioma. Differential diagnosis between paragangliomas and unusual types of pituitary adenomas, especially null-cell adenomas, is made by presence of cell nests (Zellballen) in paraganglioma, lack of immunopositivity for pituitary hormones, cytoplasmic immunopositivity for chromogranin A and neuron-specific enolase, and immunonegativity for cytokeratin 19, cytokeratin 20 and endomysial antibody. In the case of a mass in the sellar region, paraganglioma, although rare, should be included in the differential diagnosis.en10.1111/j.1440-1789.2008.00885.xinfo:eu-repo/semantics/closedAccessneoplasmparagangliomapheochromocytomasellar tumorArticle285550547184102712-s2.0-49749107629Q2WOS:000258409000013Q3