Avci, OnurGundogdu, OguzBalci, FatihTekcan, Muhammed Nail2024-10-262024-10-2620241022-386X1681-7168https://doi.org/10.29271/jcpsp.2024.01.5https://hdl.handle.net/20.500.12418/28609Objective: To investigate postoperative analgaesic efficacy of modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) and its effect on opioid consumption in patients undergoing laparoscopic cholecystectomy (LC) surgery.Study Design: Randomised, controlled trial.Place and Duration of the Study: Department of Anaesthesiology and Reanimation, Sivas Cumhuriyet University, Sivas, Turkiye, from April to May 2023. Methodology: The study was conducted in two randomised groups: M-TAPA (n = 21) and control group (CG) (no block) (n = 21). All patients had standard general anaesthesia. M-TAPA patients had bilateral M-TAPA block with 0.25% bupivacaine (total volume, 40 ml) at the end of the surgery. In contrast, CG patients had only tramadol for postoperative pain. A numerical rating scale (NRS) and visual analogue scale (VAS) were used for postoperative pain assessment. Total tramadol consumption was calculated.Results: M-TAPA's NRS and VAS scores were lower in postoperative 24 hours (p<0.05). Total tramadol consumption was 116.67 +/- 32.91 mg in CG and 35.71 +/- 39.19 mg in M-TAPA (p<0.001).Conclusion: Bilateral M-TAPA block for postoperative pain control after LC surgery provided effective analgaesia for up to 24 hours and reduced total opioid consumption. Although the M-TAPA block is a novel approach, it will be a part of multimodal analgaesia for routine postoperative pain management in abdominal surgeries. However, more studies with higher numbers of patients will be needed.en10.29271/jcpsp.2024.01.5info:eu-repo/semantics/closedAccessAnalgaesiaBupivacaineLaparoscopic cholecystectomyNerve blockPain managementArticle341105381859522-s2.0-85182019291Q3WOS:001140254200006N/A