Browsing by Author "Karakus, Savas"
Now showing items 1-20 of 26
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Amniotic Membrane-Coated Polypropylene Mesh for the Repair of Incisional Hernia: An Experimental Study In a Rat Model of Abdominal Wall Defect
Soylu, Sinan; Yildiz, Caglar; Bozkurt, Birkan; Karakus, Savas; Kurt, Begum; Kurt, Atilla (KOWSAR PUBL, 2018)Background: Incisional hernia repairs are among common abdominal wall surgeries, can be primarily required or being reconstructed using a synthetic or biological material. Objectives: This study aimed at evaluating ... -
The Association of Plasminogen Activator Inhibitor Type 1 (PAI-1) Level and PAI-1 4G/5G Gene Polymorphism with the Formation and the Grade of Endometrial Cancer
Yildirim, Malik Ejder; Karakus, Savas; Kurtulgan, Hande Kucuk; Kilicgun, Hasan; Ersan, Serpil; Bakir, Sevtap (SPRINGER/PLENUM PUBLISHERS, 2017)Plasminogen activator inhibitor type 1 (PAI-1) is a serine protease inhibitor (Serpine 1), and it inhibits both tissue plasminogen activator and urokinase plasminogen activator which are important in fibrinolysis. We aimed ... -
Comparison of Effectiveness of Laminaria versus Vaginal Misoprostol for Cervical Preparation Before Operative Hysteroscopy in Women of Reproductive Age: A Prospective Randomized Trial
Karakus, Savas; Akkar, Ozlem Bozoklu; Yildiz, Caglar; Yenicesu, Gonca Imir; Cetin, Meral; Cetin, Ali (ELSEVIER SCIENCE INC, 2016)Study Objective: To compare the effectiveness and safety of intracervical laminaria dilator versus intravaginal misoprostol administered before surgery to facilitate cervical dilation before operative hysteroscopy. Design: ... -
Comparison of maternal serum vitamin D and paraoxonase 1 levels and neutrophil to lymphocyte ratios of preeclamptic and severe preeclamptic, and normal pregnant women
Akkar, Ozlem Bozoklu; Sancakdar, Enver; Karakus, Savas; Yildiz, Caglar; Arslan, Murat; Yucel, Hasan; Ozcelik, Fatma; Yenicesu, Ayse Gonca Imir; Cetin, Meral; Cetin, Ali (E-CENTURY PUBLISHING CORP, 2016)Preeclampsia is one of the most common causes of maternal and neonatal morbidity and mortality worldwide. We aimed to evaluate the diagnostic values of maternal serum levels of 25-hydroxyvitamin D and paraoxonase 1 (PON1) ... -
Effect of imatinib on growth of experimental endometriosis in rats
Yildiz, Caglar; Kacan, Turgut; Akkar, Ozlem Bozoklu; Karakus, Savas; Seker, Metin; Kacan, Selen Baloglu; Ozer, Hatice; Cetin, Ali (ELSEVIER SCIENCE BV, 2016)Objective: Currently, medical and surgical treatment options for endometriosis are limited due to suboptimal efficacy, and also safety and tolerance issues. Long-term use of gonadotrophin-releasing hormone analogs, androgenes, ... -
The Effects of Erzincan Grape (Vitis vinifera spp., Cimin) and Benzothiazol on a Coenorhabditis elegans Organism Model
Ozpinar, Hulya; Ozpinar, Necati; Karakus, Savas (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2017)Background: Grapes and their products are known to have been used for the treatment of diseases throughout history. Objective: It was aimed to investigate the effects of Erzincan Cimin grapes on an organism model of ... -
Effects of Pazopanib, Sunitinib, and Sorafenib, Anti-VEGF Agents, on the Growth of Experimental Endometriosis in Rats
Yildiz, Caglar; Kacan, Turgut; Akkar, Ozlem Bozoklu; Karakus, Savas; Kacan, Selen Baloglu; Ozer, Hatice; Cetin, Ali (SAGE PUBLICATIONS INC, 2015)We aimed to compare the effects of pazopanib, sunitinib, and sorafenib on endometriotic tissue morphology and histological characteristics as well as ovarian reserve in a rat model. Experimental endometriosis was established ... -
Elevated Serum CD95/FAS and HIF-1 alpha Levels, but Not Tie-2 Levels, May Be Biomarkers in Patients With Severe Endometriosis: A Preliminary Report
Karakus, Savas; Sancakdar, Enver; Akkar, Ozlem; Yildiz, Caglar; Demirpence, Ozlem; Cetin, Ali (ELSEVIER SCIENCE INC, 2016)Study Objective: To evaluate serum values of cluster of differentiation 95 (CD95/FAS), hypoxia-inducible factor 1-alpha (HIF-1 alpha), and tyrosine kinase receptor 2 (Tie-2) as possible biomarkers of disease presence and ... -
Evaluation of Maternal Serum 25-Hydroxyvitamin D, Paraoxonase 1 Levels, and Neutrophil-to-Lymphocyte Ratio in Spontaneous Preterm Birth
Akkar, Ozlem Bozoklu; Sancakdar, Enver; Karakus, Savas; Yildiz, Caglar; Akkar, Ismail; Arslan, Murat; Sahin, Irfan Oguz; Yenicesu, Ayse Gonca Imir; Cetin, Ali (INT SCIENTIFIC LITERATURE, INC, 2016)Background: The aim of this study was to evaluate the association of maternal serum 25-hydroxyvitamin D, paraoxonase 1, and neutrophil-to-lymphocyte ratio in women having early spontaneous preterm birth without clinical ... -
Evaluation of ovarian reserve using anti-mullerian hormone and antral follicle count in Sjogren's syndrome: Preliminary study
Karakus, Savas; Sahin, Ali; Durmaz, Yunus; Aydin, Huseyin; Yildiz, Caglar; Akkar, Ozlem; Dogan, Mansur; Cengiz, Ahmet; Cetin, Meral; Cetin, Ali (WILEY, 2017)AimThe aim of this study was to determine ovarian reserve status using anti-mullerian hormone (AMH) level and antral follicle count (AFC) in patients with Sjogren's syndrome (SS). MethodsTwenty-four women with SS diagnosed ... -
Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer
Oz, Muhammed; Karakus, Savas; Yildirim, Malik; Bagci, Binnur; Sari, Ismail; Bagci, Gokhan; Yildiz, Caglar; Akkar, Ozlem; Cetin, Ali; Yanik, Ali (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2018)Aim: Although several associations were found between Dicer rs3742330 single nucleotide polymorphism (SNP) and development and prognosis of some epithelial cancers, relationship between the SNP rs3742330 and endometrial ... -
Hypogastric artery ligation for obstetrical hemorrhage: clinical experience in a tertiary care center
Yildiz, Caglar; Bozoklu Akkar, Ozlem; Karakus, Savas; Cetin, Ali; Yanik, Ali (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2015)Background/aim: Several authorities advocate the use of hypogastric artery ligation (HAL) in the treatment of cases of obstetrical hemorrhage related to uterine atony or placenta accreta. We assessed the morbidity and ... -
Ovarian Reserve Assessment in Celiac Patients of Reproductive Age
Cakmak, Erol; Karakus, Savas; Demirpence, Ozlem; Coskun, Banu Demet (INT SCIENTIFIC LITERATURE, INC, 2018)Background: This study aimed to investigate ovarian reserve in patients of reproductive age with Celiac disease (CD) using anti-Mullerian hormone (AMH) levels, antral follicle counts (AFCs), and ovarian volume. Material/Methods: ... -
Ovarian reserve is preserved in Behcet's disease
Sahin, Ali; Karakus, Savas; Durmaz, Yunus; Yildiz, Caglar; Aydin, Huseyin; Cengiz, Ahmet Kivanc (WILEY, 2017)AimTo compare ovarian reserve with anti-mullerian hormone (AMH) levels, antral follicle counts (AFCs) and ovarian volume in patients with Behcet's disease (BD) and healthy subjects. MethodThis study included 35 women with ... -
Primary Sjogren's Syndrome Adversely Affects the Female Sexual Function Assessed by the Female Sexual Function Index: A Case-Control Study
Yildiz, Caglar; Karakus, Savas; Bozoklu Akkar, Ozlem; Sahin, Ali; Bozkurt, Birkan; Yanik, Ali (TURKISH LEAGUE AGAINST RHEUMATISM, 2017)Objectives: This study aims to evaluate the sexual function of females with primary Sjgren's syndrome (pSS) in comparison to healthy females by using the Female Sexual Function Index (FSFI). Patients and methods: This ... -
Prophylactic hypogastric artery ligation in surgery for placental invasion disorders
Kostu, Bulent; Ozer, Alev; Ercan, Onder; Bakacak, Murat; Karakus, Savas; Keten, Hamit (E-CENTURY PUBLISHING CORP, 2016)Objective: To determine the effectiveness of prophylactic hypogastric artery ligation (HAL) on the bleeding control in surgeries of placental invasion anomalies. Study design: In this study, an evaluation was made of the ... -
Prospective study of laminaria, vaginal misoprostol, and mechanical dilator applications before surgical intervention in first-trimester pregnant women with missed abortion
Karakus, Savas; Genc, Serife Ozlem; Uludag, Semih; Oksasoglu, Bugra; Sonmez, Gamze; Yildiz, Caglar; Cetin, Ali (AVES, 2018)Objective: We aimed to compare the efficacies of laminaria, vaginal misoprostol, and mechanical dilator applications before surgical intervention with regard to the optimal cervical dilation and severity of pain in ... -
Renalase gene polymorphism is associated with increased blood pressure in preeclampsia
Bagci, Binnur; Karakus, Savas; Bagci, Gokhan; Sancakdar, Enver (ELSEVIER SCI LTD, 2016)Background: Renalase is a novel enzyme that degrades circulating catecholamines. We aimed to investigate the role of rs2576178 and rs10887800 polymorphisms of the renalase gene in preeclampsia (PE) patients Methods: This ... -
Role of MTHFR gene polymorphisms, serum tissue inhibitor of metalloproteinases-1, thymus chemokine-1 and thrombospondin-1 in endometrial cancer
Yildirim, Malik Ejder; Kilicgun, Hasan; Kurtulgan, Hande Kucuk; Karakus, Savas; Ersan, Serpil; Bakir, Sevtap; Sezgin, Ilhan (E-CENTURY PUBLISHING CORP, 2016)The aim of this study was to evaluate the relationship between the MTHFR gene variants (677 C -> T and 1298 A -> C), serum tissue metalloproteinases inhibitor (TIMP-1), thrombospondin-1 (TSP-1), thymus chemokine-1 (TCK-1) ...