Browsing by Author "Toker, Hulya"
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Alendronate enhances osseous healing in a rat calvarial defect model
Toker, Hulya; Ozdemir, Hakan; Ozer, Hatice; Eren, Kaya (PERGAMON-ELSEVIER SCIENCE LTD, 2012)Aim: The aim of this study was to evaluate the effect of alendronate on osseous wound healing in an experimental model. Methods: Critical size defects were created in calvaria of 40 male Wistar rats. The animals were divided ... -
ANALYSIS OF IL-6, IL-10 AND NF-kappa B GENE POLYMORPHISMS IN AGGRESSIVE AND CHRONIC PERIODONTITIS
Toker, Hulya; Gorgun, Emine Pirim; Korkmaz, Ertan Mahir (NATL INST PUBLIC HEALTH, 2017)Objective: Pro-inflammatory cytokines, interleukin-6 (IL-6), demonstrated to be suppressed by interleukin-10 (IL-10) are known to be regulated by the transcription factor nuclear factor-kappa B(NF-kappa B). The aim of this ... -
A comparative evaluation of the systemic and local alendronate treatment in synthetic bone graft: a histologic and histomorphometric study in a rat calvarial defect model
Toker, Hulya; Ozdemir, Hakan; Ozer, Hatice; Eren, Kaya (ELSEVIER SCIENCE INC, 2012)Objective. The purpose of this study was to compare the relative efficacy of systemic and local alendronate treatment of synthetic bone graft in a rat calvarial defect model. Study Design. Forty Wistar rats were divided ... -
Dramatic oral findings belonging to a pica patient: A case report
Toker, Hulya; Ozdemir, Hakan; Ozan, Fatih; Turgut, Mehmet; Goze, Fahrettin; Sencan, Mehmet; Kantarci, Alpdogan (WILEY, 2009)Pica is a compulsive eating of non-nutritive substances and can have serious medical implications. The causes are not known, but the symptom is often associated iron-deficiency. Pica is an under-diagnosed problem. Although ... -
The effect of boron on alveolar bone loss in osteoporotic rats
Toker, Hulya; Ozdemir, Hakan; Yuce, Hatice Bald; Goze, Fahrettin (ELSEVIER TAIWAN, 2016)Background/purpose: The aim of this study is to investigate the effects of systemically administered boric acid on osteoporosis-related bone alterations, alveolar bone loss, receptor activator of nuclear factor kappa-b ... -
Effect of Chronic Periodontitis on Serum and Gingival Crevicular Fluid Oxidant and Antioxidant Status in Patients With Familial Mediterranean Fever Before and After Periodontal Treatment
Bostanci, Vildan; Toker, Hulya; Senel, Soner; Ozdemir, Hakan; Aydin, Huseyin (AMER ACAD PERIODONTOLOGY, 2014)Background: The aim of this study is to investigate the impact of periodontal status on oxidant/antioxidant status in patients with chronic periodontitis (CP) who experienced familial Mediterranean fever (FMF) and their ... -
The effect of colchicine on alveolar bone loss in ligature-induced periodontitis
Toker, Hulya; Yuce, Hatice Balci; Yildirim, Ali; Tekin, Mehmet Bugrul; Gevrek, Fikret (SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2019)Colchicine is widely used in the treatment of several inflammatory diseases due to its anti-inflammatory effect, but effects on bone metabolism are unclear. The aim of this study was to evaluate the effects of systemical ... -
Effect of meloxicam on gingival crevicular fluid IL-1beta and IL1 receptor antagonist levels in subjects with chronic periodontitis, and its effects on clinical parameters
Toker, Hulya; Marakoglu, Ismail; Poyraz, Omer (SPRINGER HEIDELBERG, 2006)The aim of the present study was to determine the effects of meloxicam after initial periodontal treatment on interleukin-1beta (IL-1 beta) and IL-1 receptor antagonist (IL-1ra) in gingival crevicular fluid (GCF) and ... -
Effect of periodontal treatment on IL-1 beta, IL-1ra, and IL-10 levels in gingival crevicular fluid in patients with aggressive periodontitis
Toker, Hulya; Poyraz, Omer; Eren, Kaya (WILEY, 2008)Aim:The aim of this study was to examine the effect of phase I periodontal treatment on the levels of interleukin (IL)-1 beta, IL-1ra, and IL-10 in gingival crevicular fluid (GCF) in patients with generalized aggressive ... -
The effects of IL-10 gene polymorphism on serum, and gingival crevicular fluid levels of IL-6 and IL-10 in chronic periodontitis
Toker, Hulya; Gorgun, Emine Pirim; Korkmaz, Ertan Mahir; Yuce, Hatice Balci; Poyraz, Omer (UNIV SAO PAULO FAC ODONTOLOGIA BAURU, 2018)Objective: Anti-inflammatory cytokines play a crucial role in periodontitis by inhibiting synthesis of pro-inflammatory cytokines. The purpose of this study was to evaluate the effect of interleukin-10 (-597) gene polymorphism ... -
The effects of non-surgical periodontal therapy on oxidant and anti-oxidant status in smokers with chronic periodontitis
Akpinar, Aysun; Toker, Hulya; Ozdemir, Hakan; Bostanci, Vildan; Aydin, Huseyin (PERGAMON-ELSEVIER SCIENCE LTD, 2013)Aim: The aim of this study was to determine the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) and serum oxidant-antioxidant levels in smoking and non-smoking patients with chronic ... -
Efficiency of Low-Level Laser Therapy in Reducing Pain Induced by Orthodontic Forces
Bicakci, Ali Altug; Kocoglu-Altan, Burcu; Toker, Hulya; Mutaf, Ilhan; Sumer, Zeynep (MARY ANN LIEBERT, INC, 2012)Objective: The aim of this study was to investigate the effect of low-level laser therapy (LLLT) on reducing post-adjustment orthodontic pain via evaluation of gingival crevicular fluid (GCF) composition changes at the ... -
Evaluation of IL-1 beta, IL-1ra, and IL-10 levels and outcome of periodontal therapy in chronic periodontitis with familial Mediterranean fever
Bostanci, Vildan; Toker, Hulya; Senel, Soner; Poyraz, Omer; Akpinar, Aysun; Gorgun, Emine Pirim; Bakar, Olcay (SPRINGER HEIDELBERG, 2017)This study aimed to examine the IL-1 beta, IL-1ra, and IL-10 cytokine levels in gingival crevicular fluid (GCF) and serum of familial Mediterranean fever (FMF) and chronic periodontitis (CP) patients, and their response ... -
The histopathological and morphometric investigation of the effects of systemically administered boric acid on alveolar bone loss in ligature-induced periodontitis in diabetic rats
Yuce, Hatice Balci; Toker, Hulya; Goze, Fahrettin (TAYLOR & FRANCIS LTD, 2014)Objective. The purpose of this study was to evaluate the effects of systemically administered boric acid on alveolar bone loss, histopathological changes and oxidant/antioxidant status in ligature-induced periodontitis in ... -
IL-6 and IL-10 gene polymorphisms in patients with aggressive periodontitis: effects on GCF, serum and clinic parameters
Gorgun, Emine Pirim; Toker, Hulya; Korkmaz, Ertan Mahir; Poyraz, Omer (SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2017)Genetic variations observed in cytokines affect periodontitis susceptibility. The aim of this study was to investigate interleukin (IL)-6(-174) and IL-10(-597) gene polymorphisms in generalized aggressive periodontitis ... -
Influence of smoking on interleukin-1beta level, oxidant status and antioxidant status in gingival crevicular fluid from chronic periodontitis patients before and after periodontal treatment
Toker, Hulya; Akpinar, Aysun; Aydin, Huseyin; Poyraz, Omer (WILEY-BLACKWELL, 2012)Toker H, Akpinar A, Aydin H, Poyraz O. Influence of smoking on interleukin-1beta level, oxidant status and antioxidant status in gingival crevicular fluid from chronic periodontitis patients before and after periodontal ... -
A ligneous periodontitis and conjunctival lesions in a patient with plasminogen deficiency
Toker, Hulya; Toker, Mustafa Ilker; Goze, Fahrettin; Turgut, Mehmet; Yilmaz, Abdulkerim (MOSBY-ELSEVIER, 2007)Destructive membranous periodontal disease is a rare and poorly defined entity that is a part of a systemic disease due to accumulation of fibrin material. The disease is characterized by gingival enlargement and periodontal ... -
A morphometric and histopathologic evaluation of the effects of propolis on alveolar bone loss in experimental periodontitis in rats
Toker, Hulya; Ozan, Fatih; Ozer, Hatice; Ozdemir, Hakan; Eren, Kaya; Yeler, Hasan (AMER ACAD PERIODONTOLOGY, 2008)Background: Propolis collected by honeybees from various plant sources is a resinous hive product possessing a broad spectrum of biologic activities. Propolis has been used extensively in the diet to improve health and ... -
N-Acetylcysteine, a Thiol Antioxidant, Decreases Alveolar Bone Loss in Experimental Periodontitis in Rats
Toker, Hulya; Ozdemir, Hakan; Eren, Kaya; Ozer, Hatice; Sahin, Gonul (AMER ACAD PERIODONTOLOGY, 2009)Background: The purpose of this study was to analyze the morphometric and histopathologic changes associated with experimental periodontitis in rats in response to systemic administration of N-acetylcysteine (NAC). Methods: ... -
A Novel Platelet Concentrate: Titanium-Prepared Platelet-Rich Fibrin
Tunali, Mustafa; Ozdemir, Hakan; Kucukodaci, Zafer; Akman, Serhan; Yaprak, Emre; Toker, Hulya; Firatli, Erhan (HINDAWI LTD, 2014)We developed a new product called titanium-prepared platelet-rich fibrin (T-PRF). The T-PRF method is based on the hypothesis that titanium may be more effective in activating platelets than the silica activators used with ...