Browsing by Author "Kaya, T"
Now showing items 21-27 of 27
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Inhibitory effects of isradipine on spontaneous and oxytocin- and carbachol-stimulated contractions of rat myometrium
Cetin, M; Kaya, T; Cetin, A; Sarioglu, Y (KARGER, 1998)Our aim was to investigate the effect of isradipine, a second-generation calcium channel blocker, on spontaneous and oxytocin- and carbachol-stimulated contractions of myometrium isolated from nonpregnant and pregnant rats. ... -
Interactive effect of sevoflurane with isradipine or inclomethacin on spontaneous contractile activity of isolated pregnant rat myometrium
Gursoy, S; Kaya, T; Kunt, N; Karadas, B; Bagcivan, I; Kafali, H (ELSEVIER SCI LTD, 2004)Volatile anesthetics, calcium antagonists and non-steroidal anti-inflammatory drugs inhibit contractile activity of myometrial smooth muscle. The aim of this study was to investigate the interactive effect of sevoflurane ... -
Investigation of the mechanism of nicotine-induced relaxation on the sheep sphincter of Oddi
Bagcivan, I; Kaya, T; Turan, M; Goktas, S; Demirel, Y; Gursoy, S (CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2004)Possible mechanisms for nicotine-induced relaxation were investigated in the isolated sheep's sphincter of Oddi. Sheep's sphincter of Oddi rings were mounted in tissue bath with modified Krebs-Henseleit solution and aerated ... -
Prevention of postoperative adhesion formation in rat uterine horn model by nimesulide: a selective COX-2 inhibitor
Guvenal, T; Cetin, A; Ozdemir, H; Yanar, O; Kaya, T (OXFORD UNIV PRESS, 2001)BACKGROUND: Pelvic surgery is one of the main causes of intraperitoneal (i.p.) adhesions that create various medical problems including pelvic pain, bowel obstructions and female infertility. A rat model was used to ... -
The role of K+ channels on the inhibitor effect of sevoflurane in pregnant rat myometrium
Kafali, H; Kaya, T; Gursoy, S; Bagcivan, I; Karadas, B; Sarioglu, Y (LIPPINCOTT WILLIAMS & WILKINS, 2002)Volatile anesthetics and K+ channel openers inhibit spontaneous contractions in myometrial smooth muscle. Volatile anesthetics modulate K+ channel activity We investigated the role of two K+ channel blockers on the effect ... -
Vasorelaxant effect of opioid analgesics on the isolated human radial artery
Gursoy, S; Bagcivan, I; Yildirim, MK; Berkan, O; Kaya, T (CAMBRIDGE UNIV PRESS, 2006)Background and objective: Arterial grafts are prone to vasospasm. Opiold analgesics are commonly used in the perioperative course of cardiac surgical procedures. Therefore, we investigated the direct effects of morphine, ... -
YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits the spontaneous contractions of isolated pregnant rat myometrium
Cetin, A; Kaya, T; Demirkoprulu, N; Karadas, B; Duran, B; Cetin, M (JAPANESE PHARMACOLOGICAL SOC, 2004)The aim of this study was to investigate the effect of YC-1 (3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole) on spontaneous contractions and levels of cyclic GMP (cGMP) of myometrial strips isolated from pregnant rats. ...