Browsing by Author "Arslan, Serdal"
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Association between MMP-3 and MMP-9 polymorphisms and coronary artery disease
Beton, Osman; Arslan, Serdal; Acar, Burak; Ozbilum, Nil; Berkan, Ocal (SPANDIDOS PUBL LTD, 2016)Matrix metalloproteinase (MMP)-3 and MMP-9 polymorphisms are characterized by plaque stability in coronary arteries. The aim of the current study was to investigate the 5A/6A polymorphism in the MMP-3 gene and C/T polymorphism ... -
Association between NF-kappa BI and NF-kappa BIA polymorphisms and coronary artery disease
Arslan, Serdal; Korkmaz, Ozge; Ozbilum, Nil; Berkan, Ocal (SPANDIDOS PUBL LTD, 2015)Coronary artery disease (CAD) is the leading cause of fatalities worldwide. Nuclear factor (NF)-kappa B is a transcription factor that controls cell proliferation, differentiation and immunity. To the best of our knowledge, ... -
Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129
Gomes, Clarissa Pedrosa da Costa; Agg, Bence; Andova, Andrejaana; Arslan, Serdal; Baker, Andrew; Bartekova, Monika; Beis, Dimitris; Betsou, Fay; Wettinger, Stephanie Bezzina; Bugarski, Branko; Condorelli, Gianluigi; da Silva, Gustavo Jose Justo; Danilin, Sabrina; de Gonzalo-Calvo, David; Buil, Alfonso; Carmo-Fonseca, Maria; Enguita, Francisco J.; Felekkis, Kyriacos; Ferdinandy, Peter; Gyoengyoesi, Mariann; Hackl, Matthias; Karaduzovic-Hadziabdic, Kanita; Hellemans, Jan; Heymans, Stephane; Hlavackova, Marketa; Hoydal, Morten Andre; Jankovic, Aleksandra; Jusic, Amela; Kardassis, Dimitris; Kerkela, Risto; Kuster, Gabriela M.; Lakkisto, Paivi; Leszek, Przemyslaw; Lustrek, Mitja; Maegdefessel, Lars; Martelli, Fabio; Novella, Susana; O'Brien, Timothy; Papaneophytou, Christos; Pedrazzini, Thierry; Pinet, Florence; Popescu, Octavian; Potocnjak, Ines; Robinson, Emma; Sasson, Shlomo; Scholz, Markus; Simionescu, Maya; Stoll, Monika; Varga, Zoltan V.; Vinciguerra, Manlio; Xuereb, Angela; Yilmaz, Mehmet Birhan; Emanueli, Costanza; Devaux, Yvan (MDPI, 2019)Cardiovascular disease (CVD) remains the leading cause of death worldwide and, despite continuous advances, better diagnostic and prognostic tools, as well as therapy, are needed. The human transcriptome, which is the set ... -
Decreased FENDRR and LincRNA-p21 expression in atherosclerotic plaque
Cekin, Nilgun; Ozcan, Arzu; Goksel, Sabahattin; Arslan, Serdal; Pmarbasi, Ergun; Berkan, Ocal (TURKISH SOC CARDIOLOGY, 2018)Objective: Cardiovascular diseases are the most important cause of mortality worldwide, particularly atherosclerosis. Recently, lncRNAs affecting atherosclerotic progression have been reported in vascular smooth muscle ... -
Determination of chemical profile, antioxidant, DNA damage protection and antiamoebic activities of Teucrium polium and Stachys iberica
Tepe, Bektas; Degerli, Serpil; Arslan, Serdal; Malatyali, Erdogan; Sarikurkcu, Cengiz (ELSEVIER SCIENCE BV, 2011)This work deals with the evaluation of in vitro antioxidant, DNA preventing and antiamoebic activities of the water extracts of Teucrium polium and Stachys iberica. In all systems, T. polium extract exhibited excellent ... -
Effect of TLR10 (2322A/G, 720A/C, and 992T/A) polymorphisms on the pathogenesis of Crimean Congo hemorrhagic fever disease
Kizildag, Sibel; Arslan, Serdal; Ozbilum, Nil; Engin, Aynur; Bakir, Mehmet (WILEY, 2018)Crimean Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by the Crimean Congo hemorrhagic fever virus (CCHFV). Toll-like receptors (TLRs) are type 1 transmembrane proteins of immune cells that play a critical ... -
Effects of MPO-463G/A and -129G/A polymorphisms on coronary artery disease risk and patient survival in a Turkish population
Arslan, Serdal; Berkan, Ocal; Bayyurt, Burcu; Beton, Osman; Sahin, Nil Ozbilum; Aydemir, Eylem Itir (SPANDIDOS PUBL LTD, 2017)Myeloperoxidase (MPO) is an oxidative hemoprotein compound expressed in polymorphonuclear leukocytes that contributes to inflammatory responses. Coronary artery disease (CAD), as the most prevalent form of heart disease, ... -
FOXP3 rs3761548 polymorphism is associated with knee osteoarthritis in a Turkish population
Cekin, Nilgun; Pinarbasi, Ergun; Bildirici, Aslihan Esra; Donmez, Gonca; Oztemur, Zekeriya; Bulut, Okay; Arslan, Serdal (WILEY, 2018)Aim: Functional polymorphisms located in FOXP3 intron 1 was recently found to be associated with rheumatoid arthritis (RA). Although RA is an autoimmune disease, there is supporting evidence that activated maladaptive ... -
Genetic Polymorphisms of Sulfotransferases (SULT1A1 and SULT1A2) in a Turkish Population
Arslan, Serdal (SPRINGER/PLENUM PUBLISHERS, 2010)Sulfotransferases (SULTs) play a significant role in the biotransformation of a variety of xenobiotics and endogenous compounds. SULTs are genetically polymorphic enzymes; to date, 12 human cytosolic SULT isoforms have ... -
Genetic Structure of Brown Trout (Salmo trutta) Populations from Turkey Based on Microsatellite Data
Arslan, Serdal; Bardakci, Fevzi (SPRINGER/PLENUM PUBLISHERS, 2010)This present study investigated micro- and macro-geographic microsatellite DNA variations using five polymorphic microsatellite loci from 27 brown trout populations in Turkey. Average number of alleles and average observed ... -
HULC and 7SL RNA expression levels in patients with Crimean-Congo hemorrhagic fever
Bayyurt, Burcu; Arslan, Serdal; Engin, Aynur; Bakir, Mehmet (WILEY, 2018)Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by the Crimean-Congo hemorrhagic fever virus. Long non-coding RNAs (lncRNAs) are generally classified as transcripts longer than 200 nucleotides (nt). ... -
An investigation of the relationship between SULT1A1 Arg(213)His polymorphism and lung cancer susceptibility in a Turkish population
Arslan, Serdal; Silig, Yavuz; Pinarbasi, Hatice (WILEY-BLACKWELL, 2009)Human sulfotransferase 1A1 (SULT1A1), the most expressed isoform of the phenol SULT1 subfamily, is an important member of sulfotransferase superfamily. A transition, G to A at position 638, in SULT1A1 gene, results in ... -
Is There Any Relationship Between Toll-Like Receptor 3 c.1377C/T and-7C/A Polymorphisms and Susceptibility to Crimean Congo Hemorrhagic Fever?
Engin, Aynur; Arslan, Serdal; Ozbilum, Nil; Bakir, Mehmet (WILEY-BLACKWELL, 2016)Crimean-Congo hemorrhagic fever (CCHF) is an infectious disease that is caused by CCHF virus. A family of transmembrane receptors called as Toll-like receptors (TLRs) selectively acts in recognizing a wide range of microbial ... -
Long non-coding RNAs in the atherosclerotic plaque
Arslan, Serdal; Berkan, Ocal; Lalem, Torkia; Ozbilum, Nil; Goksel, Sabahattin; Korkmaz, Ozge; Cetin, Nilgun; Devaux, Yvan (ELSEVIER IRELAND LTD, 2017)Background and aims: Genetic and environmental factors are important components of the development of atherosclerosis. Long non-coding RNA (lncRNAs) have emerged as regulators of multiple pathophysiological pathways in the ... -
MicroRNA-221/222 expression in atherosclerotic coronary artery plaque versus internal mammarian artery and in peripheral blood samples
Bildirici, Aslihan Esra; Arslan, Serdal; Sahin, Nil Ozbilum; Berkan, Ocal; Beton, Osman; Yilmaz, Mehmet Birhan (TAYLOR & FRANCIS LTD, 2018)Background: Atherosclerosis is a disease of the arterial wall with predilection to some sites on others. MicroRNAs (miRNAs) are a class of the non-coding RNAs regulating the target gene expression at post-transcriptional ... -
Myeloperoxidase G-463A polymorphism and risk of lung and prostate cancer in a Turkish population
Arslan, Serdal; Pinarbasi, Hatice; Silig, Yavuz (SPANDIDOS PUBL LTD, 2011)Myeloperoxidase (M PO) is a phase I enzyme that can bioactivate many specific procarcinogens, including polycyclic aromatic hydrocarbons and aromatic amines. The MPO gene contains a common single nucleotide polymorphism, ... -
The optimization of aDNA extraction protocol and sex determination of Bronze Age individuals from Oylum Hoyuk (Kilis, Turkey)
Arslan, Serdal; Acikkol, Aysen; Korkmaz, Ertan Mahir (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2011)Oylum Hoyuk falls within the borders of the province of Kills, located in the southern part of Turkey. It is an important Bronze Age settlement dating back to 5500 BC. In this study, the sex of 36 individuals found in Oylum ... -
Relationship between NF-kappa B1 and NF-kappa BIA genetic polymorphisms and Crimean-Congo hemorrhagic fever
Arslan, Serdal; Engin, Aynur (INFORMA HEALTHCARE, 2012)Background: Crimean-Congo hemorrhagic fever (CCHF) is an acute viral hemorrhagic fever caused by the Crimean-Congo hemorrhagic fever virus (CCHFV). Nuclear factor (NF)-kappa B regulates the expression of hundreds of genes, ... -
The Role of NF-kappa B1A Promoter Polymorphisms on Coronary Artery Disease Risk
Ozbilum, Nil; Arslan, Serdal; Berkan, Ocal; Yanartas, Mehmed; Aydemir, Eylem Itir (WILEY-BLACKWELL, 2013)Coronary artery disease (CAD), which is now regarded as a chronic inflammatory disease, is the leading cause of death worldwide. Nuclear factor (NF)-B is a transcription factor that plays an important role in the regulation ... -
Screening of the antioxidant, antimicrobial and DNA damage protection potentials of the aqueous extract of Asplenium ceterach DC
Berk, Seyda; Tepe, Bektas; Arslan, Serdal; Sarikurkcu, Cengiz (ACADEMIC JOURNALS, 2011)In this study, in vitro antioxidant, antimicrobial and DNA damage protection potentials of the aqueous extract of Asplenium ceterach was firstly evaluated in addition to its total phenolic and flavonoid contents. Antioxidant ...