Browsing by Author "Bagci, Gokhan"
Now showing items 1-20 of 22
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Angiotensin-Converting Enzyme (ACE) I/D and Alpha-Adducin (ADD1) G460W Gene Polymorphisms in Turkish Patients with Severe Chronic Tinnitus
Yuce, Salim; Sancakdar, Enver; Bagci, Gokhan; Koc, Sema; Kurtulgan, Hande Kucuk; Bagci, Binnur; Dogan, Mansur; Uysal, Ismail Onder (AVES, 2016)OBJECTIVE: Tinnitus is described as a disturbing sound sensation in the absence of external stimulation. We aimed to investigate whether there is any relationship between severe chronic tinnitus and angiotensin-converting ... -
Apelin and fetuin-a may be subclinical inflammation biomarker in familial mediterranean fever: A pilot study
Sahin, Ali; Demirpence, Ozlem; Sahin, Mehtap; Bagci, Gokhan; Seven, Dogan; Dogan, Halef Okan; Camci, Ayse; Derin, Mehmet Emin; Bagci, Binnur (DERMAN MEDICAL PUBL, 2017)Aim: Positive acute-phase reactants generally increase during the attack period (AP) of familial Mediterranean fever (FMF) and return to normal range in the attack-free period (AFP). In some patients, the level of these ... -
Association of vitamin D receptor gene Taql, Fokl and Apal variants with arteriovenous fistula failure in hemodialysis patients
Huzmeli, Can; Bagci, Gokhan; Candan, Ferhan; Bagci, Binnur; Akkaya, Lale; Kayatas, Mansur (SAGE PUBLICATIONS LTD, 2018)Purpose: We investigated the influence of the vitamin D receptor gene Taql (rs731236), Apal (rs7975232), and Fokl (rs2228570) polymorphisms in arteriovenous fistula failure in hemodialysis patients. Methods: This study was ... -
Associations of fractalkine receptor (CX3CR1) and CCR5 gene variants with hypertension, diabetes and atherosclerosis in chronic renal failure patients undergoing hemodialysis
Bagci, Binnur; Bagci, Gokhan; Huzmeli, Can; Sezgin, Ilhan; Ozdemir, Ozturk (SPRINGER, 2016)We aimed to investigate the associations of fractalkine receptor (CX3CR1) V249I, T280M and CCR5-59029 A/G gene polymorphisms in chronic renal failure (CRF) subjects undergoing hemodialysis and to evaluate possible associations ... -
CCR2 Polymorphism in Chronic Renal Failure Patients Requiring Long-Term Hemodialysis
Sezgin, Ilhan; Koksal, Binnur; Bagci, Gokhan; Kurtulgan, Hande Kucuk; Ozdemir, Ozturk (JAPAN SOC INTERNAL MEDICINE, 2011)Objective A number of chemokines and chemokine receptors are produced by intrinsic renal cells as well as by infiltrating cells during renal inflammation. The CCR2 chemokine receptor mediates leukocyte chemoattraction in ... -
Evaluation of 61 Secondary Amyloidosis Patients: A Single-Center Experience from Turkey
Huzmeli, Can; Candan, Ferhan; Bagci, Gokhan; Alaygut, Demet; Bagci, Binnur; Yildiz, Esin; Kockara, Ayse Seker; Kayatas, Mansur (DERMAN MEDICAL PUBL, 2016)Aim: To evaluate demographic,clinical and laboratory characteristics. causes, MEFV gene mutations, and mortality rates of patients with secondary amyloidosis. Material and Method: 61 patients who had been diagnosed with ... -
Frequency of familial Mediterranean fever (MEFV) gene mutations in patients with biopsy-proven primary glomerulonephritis
Huzmeli, Can; Candan, Ferhan; Bagci, Gokhan; Alaygut, Demet; Yilmaz, Ali; Gedikli, Asim; Bagci, Binnur; Timucin, Meryem; Sezgin, Ilhan; Kayatas, Mansur (SPRINGER LONDON LTD, 2017)Primary glomerulopathies are those disorders that affect glomerular structure, function, or both in the absence of a multisystem disorder. We aimed to evaluate the frequency of MEFV gene mutation to show possible coexistence ... -
Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer
Oz, Muhammed; Karakus, Savas; Yildirim, Malik; Bagci, Binnur; Sari, Ismail; Bagci, Gokhan; Yildiz, Caglar; Akkar, Ozlem; Cetin, Ali; Yanik, Ali (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2018)Aim: Although several associations were found between Dicer rs3742330 single nucleotide polymorphism (SNP) and development and prognosis of some epithelial cancers, relationship between the SNP rs3742330 and endometrial ... -
Glutathione-S-Transferase Variants are not Associated With Increased Carotid Intima-Media Thickness in Turkish Familial Mediterranean Fever Patients
Gurbuz, Ozlem; Bagci, Binnur; Huzmeli, Can; Bagci, Gokhan; Candan, Ferhan (TURKISH LEAGUE AGAINST RHEUMATISM, 2016)Objectives: This study aims to evaluate the carotid intima-media thickness (CIMT) in patients diagnosed with familial Mediterranean fever (FMF) and investigate whether there is a relationship between glutathione-S-transferase ... -
Increased Levels of VEGF-A and HIF-1 alpha in Turkish Children with Crimean-Congo Hemorrhagic Fever
Sefikogullari, Murat; Kaya, Ali; Aydin, Huseyin; Sancakdar, Enver; Celik, Veysel Kenan; Bagci, Gokhan (IRANIAN SCIENTIFIC SOCIETY MEDICAL ENTOMOLOGY, 2017)Background: Crimean-Congo Hemorrhagic Fever (CCHF) is a disease characterized by serious course, including acute viral fever, ecchymosis, thrombocytopenia, liver dysfunction and high rate of mortality. Hypoxia Inducible ... -
KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients
Bagci, Binnur; Sari, Musa; Karadayi, Kursat; Turan, Mustafa; Ozdemir, Ozturk; Bagci, Gokhan (IOS PRESS, 2016)BACKGROUND: Colorectal cancer is a serious disease that causes significant morbidity and mortality in developed countries. Genetic changes, such as mutations in proto-oncogenes and DNA repair genes, and loss of function ... -
Occult Hepatitis B Prevalence in Hepatitis B Vaccinated Dialysis Patients
Huzmeli, Can; Seker, Ayse; Candan, Ferhan; Bagci, Gokhan; Akkaya, Lale; Bakici, Mustafa Zahir; Kayatas, Mansur (TURK NEFROLOJI DIYALIZ TRANSPLANTASYON DERGISI, 2018)OBJECTIVE: Occult hepatitis B (OHB) virus infection is defined as the presence of hepatitis B virus (HBV) DNA in the liver tissue or serum of subjects seronegative for hepatitis B surface antigen. OHB leads to the potential ... -
Prevalence of Fabry Disease in Familial Mediterranean Fever Patients from Central Anatolia of Turkey
Huzmeli, Can; Candan, Ferhan; Alaygut, Demet; Bagci, Gokhan; Akkaya, Lale; Bagci, Binnur; Sozmen, Eser Yildirim; Kurtulgan, Hande Kucuk; Kayatas, Mansur (SPRINGER/PLENUM PUBLISHERS, 2016)Fabry disease (FD) is a progressive, X-linked inherited disorder of glycosphingolipid metabolism due to deficient or absent lysosomal alpha-galactosidase A (AGALA) activity. FD and familial Mediterranean fever (FMF) have ... -
The protective effect of MCP-1-2518 A > G promoter polymorphism in Turkish chronic renal failure patients requiring long-term hemodialysis
Bagci, Binnur; Bagci, Gokhan; Candan, Ferhan; Ozdemir, Ozturk; Sezgin, Ilhan (SPRINGER, 2015)Monocyte chemoattractant protein-1 (MCP-1) plays a major role in the pathogenesis and progression of different types of human renal disease. Therefore, in this study, we aimed to investigate the effect of MCP-1 gene -2518 ... -
Relationship between IFNA1, IFNA5, IFNA10, and IFNA17 gene polymorphisms and Crimean-Congo hemorrhagic fever prognosis in a Turkish population range
Elaldi, Nazif; Yilmaz, Meral; Bagci, Binnur; Yelkovan, Izzet; Bagci, Gokhan; Gozel, Mustafa Gokhan; Engin, Aynur; Bakir, Mehmet; Dokmetas, Ilyas (WILEY, 2016)Crimean-Congo hemorrhagic fever (CCHF) is a fatal emerging acute viral infection. Not much is known regarding the pathogenic mechanisms and the reasons behind severe or mild disease courses in CCHF. IFN-alpha (IFNA) is one ... -
Renalase gene polymorphism is associated with increased blood pressure in preeclampsia
Bagci, Binnur; Karakus, Savas; Bagci, Gokhan; Sancakdar, Enver (ELSEVIER SCI LTD, 2016)Background: Renalase is a novel enzyme that degrades circulating catecholamines. We aimed to investigate the role of rs2576178 and rs10887800 polymorphisms of the renalase gene in preeclampsia (PE) patients Methods: This ... -
The Role of the CCR2 Gene Polymorphism in Abdominal Aortic Aneurysms
Katrancioglu, Nurkay; Manduz, Sinasi; Karahan, Oguz; Yilmaz, Mehmet Birhan; Sezgin, Ilhan; Bagci, Gokhan; Berkan, Ocal (SAGE PUBLICATIONS INC, 2011)Objective: Chronic inflammation play an important role on abdominal aortic aneurysms (AAA) formation. Chemokine receptor-2 (CCR2) is involved in regulation of the inflammatory response. However, relation between CCR2 ... -
SDF-1/CXCL12 and CXCR4 gene variants, and elevated serum SDF-1 levels are associated with preeclampsia
Karakus, Savas; Bagci, Binnur; Bagci, Gokhan; Sancakdar, Enver; Yildiz, Caglar; Akkar, Ozlem; Cetin, Ali (TAYLOR & FRANCIS INC, 2017)Objective: We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE).Methods: In total, 89 ...
