Browsing by Author "Dastan, Sevgi Durna"
Now showing items 1-13 of 13
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The effectiveness of platelet-rich plasma in an anosmia-induced mice model
Yasak, Ahmet Gorkem; Yigit, Ozgur; Server, Ela Araz; Dastan, Sevgi Durna; Gul, Mehmet (WILEY, 2018)ObjectiveIn this study, we aimed to functionally and morphologically demonstrate the effectiveness of platelet-rich plasma (PRP) on anosmia in a mouse model of anosmia. Study DesignAnimal study. MethodsA total of 16 male ... -
The effects of wireless electromagnetic fields on the activities of carbonic anhydrase and acetylcholinesterase enzymes in various tissues of rats
Kocyigit, Umit Muhammet; Taslimi, Parham; Gurses, Fatih; Soylu, Sinan; Dastan, Sevgi Durna; Gulcin, Ilhami (WILEY, 2018)The purpose of our study is to assist in understanding the effects of wireless electromagnetic waves on carbonic anhydrase (CA) and acetylcholinesterase (AChE) enzymes activities in the different tissues of the rats. For ... -
Genetic Diversity of Cyprinion macrostomus Heckel, 1843 (Teleostei: Cyprinidae) in Anatolia
Dastan, Sevgi Durna; Bardakci, Fevzi; Degerli, Naci (CENTRAL FISHERIES RESEARCH INST, 2012)In this study, the phylogenetic and phylogeographic relationships among Cyprinion macrostomus HECKEL, 1843, Cyprinion kais HECKEL, 1843 and Carasobarbus chantrei SAUVAGE, 1882 samples from Anatolia were analysed. While ... -
In Vitro Antioxidant Evaluation of Some Mannich Bases which Contain Bis-1,2,4-Triazole Derivative
Parlak, Akif Evren; Karatepe, Mustafa; Koparir, Metin; Dastan, Sevgi Durna; Alayunt, Naci Omer; Ulas, Mustafa; Keser, Serhat; Celik, Sait (CHEM SOC PAKISTAN, 2015)This study aims to examine the antioxidant effects of some Mannich bases containing bis-1, 2, 4 triazole, which are synthesized afresh. The antioxidant activities of the derivatives were measured using different methods ... -
Inhibitory effects of some drugs on carbonic anhydrase enzyme purified from Kangal Akkaraman sheep in Sivas, Turkey
Kocyigit, Umit M.; Dastan, Sevgi Durna; Taslimi, Parham; Dastan, Taner; Gulcin, Ilhami (WILEY, 2018)In this study, carbonic anhydrase (CA) enzyme was purified and characterized from blood samples of Kangal Akkaraman sheep and inhibitory properties on certain antibiotics were examined. CA purification was composed of ... -
Investigation of acetylcholinesterase and mammalian DNA topoisomerases, carbonic anhydrase inhibition profiles, and cytotoxic activity of novel bis(-aminoalkyl)phosphinic acid derivatives against human breast cancer
Dastan, Taner; Kocyigit, Umit M.; Dastan, Sevgi Durna; Kilickaya, Pakize Canturk; Taslimi, Parham; Cevik, Ozge; Koparir, Metin; Orek, Cahit; Gulcin, Ilhami; Cetin, Ahmet (WILEY, 2017)The aim of this study was to evaluate biologically active novel molecules having potentials to be drugs by their antitumor properties and by activities of apoptotic caspase and topoisomerase. Following syntheses of novel ... -
Investigation of anti-proliferative and antioxidative effects of some bis (alpha-amino) phosphinic acid derivatives
Dastan, Taner; Dastan, Sevgi Durna; Atas, Mehmet; Orek, Cahit; Koparir, Pelin; Parlak, Akif Evren; Baral, Inanc; Koparir, Metin; Cetin, Ahmet (UNIV KARACHI, 2016)Aminophosphinic acids which are organophosphorus compounds widely investigated for potential production of antibacterial, antitumor and antiviral materials. In vitro antioxidant, cytotoxic and antimicrobial activities of ... -
INVESTIGATION OF THE GENETIC STRUCTURES AND PHYLOGENETIC RELATIONSHIPS FOR THE SPECIES OF THE GENUS ANTHRISCUS PERS. (APIACEAE) DISTRIBUTED IN TURKEY, USING THE NON - CODING "TRN" REGIONS OF THE CHLOROPLAST GENOME
Sancar, Pelin Yilmaz; Civelek, Semsettin; Tekin, Mehmet; Dastan, Sevgi Durna (PAKISTAN BOTANICAL SOC, 2019)The genus Anthriscus Pers. of the family Apiaceae is a small sized genus with 16 species, distributed in the world. In Turkey it is represented by 8 taxa, distributed in 4 sections. The aim of this study was to determine ... -
Phenylthiocarbamide taste perception as a possible genetic association marker for nutritional habits and obesity tendency of people
Dastan, Sevgi Durna; Degerli, Naci; Dastan, Taner; Yildiz, Fazilet; Yildir, Yavuz; Durna, Yusuf Muhammed; Atessahin, Dilek; Karan, Tunay (UNIV KARACHI, 2015)Ability to taste Phenylthiocarbamide (PTC) a bitter molecule, is usually used to know the heritable characteristic in both genetic and physiological studies. So far, no research has yet attested whether PTC blindness ... -
ROLE OF PROPOLIS ON OXIDATIVE STRESS IN VARIOUS TISSUES OF FISH
Aldemir, Osman Selcuk; Selamoglu, Zeliha; Gulhan, Mehmet Fuat; Cakir, Oguz; Ozdemir, Ilknur; Dastan, Sevgi Durna; Dogan, Husnu (PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2014)The aim of this study was to investigate the therapeutic effects of propolis on biochemical parameters in tissues of rainbow trout (Oncorhynchus mykiss) exposed to cypermethrin. Cypermethrin is a potential toxic pollutant ... -
Synthesis and biological activities of some novel aminomethyl derivatives of 4-substituted-5-(2-thienyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones
Koparir, Metin; Orek, Cahit; Parlak, Akif Evren; Soylemez, Abdurrazak; Koparir, Pelin; Karatepe, Mustafa; Dastan, Sevgi Durna (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2013)A novel series of compounds were synthesized by cyclic condensation reaction of substituted isothiocyanate (2a-c) with 2-thiophenecarboxylic acid hydrazide (1) in the presence of ethyl alcohol, to obtain intermediate ... -
Synthesis and in vitro antioxidant evaluation of new bis(-aminoalkyl)phosphinic acid derivatives
Sarac, Kamiran; Orek, Cahit; Cetin, Ahmet; Dastan, Taner; Koparir, Pelin; Dastan, Sevgi Durna; Koparir, Metin (TAYLOR & FRANCIS LTD, 2016)Diamines were added to arylaldehydes in ethanol, which resulted in corresponding diimines. Novel bis-1-aminophosphinic acid compounds were synthesized through the interaction of diimines and hypophosphorous acid. The new ... -
Synthesis of some novel pyridine compounds containing bis-1,2,4-triazole/thiosemicarbazide moiety and investigation of their antioxidant properties, carbonic anhydrase, and acetylcholinesterase enzymes inhibition profiles
Bulut, Nilufer; Kocyigit, Umit M.; Gecibesler, Ibrahim H.; Dastan, Taner; Karci, Huseyin; Taslimi, Parham; Dastan, Sevgi Durna; Gulcin, Ilhami; Cetin, Ahmet (WILEY, 2018)Some novel derivatives of thiosemicarbazide and 1,2,4-triazole-3-thiol were synthesized and evaluated for their biological activities. The title compounds were prepared starting from readily available pyridine-2,5-dicarboxylic ...