Browsing by Author "Gokakin, Ali Kagan"
Now showing items 1-6 of 6
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The effects of sildenafil in liver and kidney injury in a rat model of severe scald burn: a biochemical and histopathological study
Gokakin, Ali Kagan; Atabey, Mustafa; Deveci, Koksal; Sancakdar, Enver; Tuzcu, Mehmet; Duger, Cevdet; Topcu, Omer (TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2014)BACKGROUND: Severe burn induces systemic inflammation and reactive oxygen species leading to lipid peroxidation which may play role in remote organs injury. Sildenafil is a selective and potent inhibitor of cyclic guanosine ... -
Evaluation of nasal mucociliary activity in iatrogenic hypothyroidism
Uysal, Ismail Onder; Gokakin, Ali Kagan; Karakus, Canan Filiz; Deveci, Koksal; Hasbek, Zekiye; Sancakdar, Enver (SPRINGER, 2013)Our aim was to evaluate the effects of iatrogenic, acute and deep hypothyroidism on nasal mucociliary clearance. A total of 46 patients undergoing total or near total thyroidectomy for differentiated thyroid cancer between ... -
Expression of FHIT, p16, p53 and EGFR as prognostic markers in thyroid tumors of uncertain malignant potential
Koc, Mustafa; Aktimur, Recep; Gokakin, Ali Kagan; Atabey, Mustafa; Koyuncu, Ayhan; Elagoz, Sahende; Topcu, Omer (ZERBINIS MEDICAL PUBL, 2015)Purpose: Thyroid tumors of uncertain malignant potential (TT-UMP) constitute a relatively new diagnosis. The purpose of this study was to analyze the relationship between immunohistochemical panels, prognostic parameters ... -
The impact of Ramadan on peptic ulcer perforation
Gokakin, Ali Kagan; Kurt, Atilla; Atabey, Mustafa; Koyuncu, Ayhan; Topcu, Omer; Aydin, Cengiz; Sen, Metin; Akgol, Gunduz (TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2012)BACKGROUND Medical treatment has played an important role in the reduction of peptic ulcer perforation (PUP). The goal of this study was to evaluate the effect of fasting on PUP. METHODS A retrospective analysis of 229 ... -
Oxidative stress markers in laparoscopic vs. open appendectomy for acute appendicitis: A double-blind randomized study
Aktimur, Recep; Gokakin, Ali Kagan; Deveci, Koksal; Atabey, Mustafa; Topcu, Omer (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2016)Background: Oxidative stress is a complicated process, which was defined as an increase in prooxidants and decrease in antioxidants caused by various mechanisms, including inflammation and surgical trauma. The association ... -
The protective effects of sildenafil in acute lung injury in a rat model of severe scald burn: A biochemical and histopathological study
Gokakin, Ali Kagan; Deveci, Koksal; Kurt, Atilla; Karakus, Boran Cihat; Duger, Cevdet; Tuzcu, Mehmet; Topcu, Omer (ELSEVIER SCI LTD, 2013)Severe burn induces biochemical mediators such as reactive oxygen species that leads to lipid peroxidation which may have a key role in formation of acute lung injury (ALI). Sildenafil is a selective and potent inhibitor ...
