Browsing by Author "Gulçin, İlhami"

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Design, synthesis, characterization, biological evaluation, and molecular docking studies of novel 1,2-aminopropanthiols substituted derivatives as selective carbonic anhydrase, acetylcholinesterase and α-glycosidase enzymes inhibitors

Huseynova, Afat; Kaya, Ruya; Taslimi, Parham; Farzaliyev, Vagif; Mammadyarova, Xadija; Sujayev, Afsun; Tüzün,Burak; Kocyigit, Umit M.; Alwasel, Saleh; Gulçin, İlhami (27.08.2020)

In the article, various substituted derivatives of 1,2-aminopropanthiol (1a–g) have been prepared by a general and efficientmethod, in one-steps, starting fromavailable thiirane and aromatic amines (aniline, o-toluidine) ...
Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from lawsone

Riaz, Muhammad Tariq; Yaqub, Muhammad; Shafiq, Zahid; Ashraf, Abida; Khalid, Muhammad; Taslimi, Parham; Tas, Recep; Tuzun, Burak; Gulçin, İlhami (5 June 202)

Some metabolic enzyme inhibitors can be used as Multi-target-Directed-Ligands (MTDL) in Medicinal chemistry therefore, synthesis and determination of alternative inhibitors are essential. In this study, novel bisnapthoquinone ...