Browsing by Author "Tüzün,Burak"
Now showing items 1-14 of 14
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1,2,3-Triazole substituted phthalocyanine metal complexes as potential inhibitors for anticholinesterase and antidiabetic enzymes with molecular docking studies
Koçyiğit, Ümit M.; Taslimi, Parham; Tüzün,Burak; Yakan, Hasan; Muğlu, Halit; Güzel, Emre (09.12.2020)In recent years, acetylcholinesterase (AChE) and a-glycosidase (a-gly) inhibition have emerged as a promising and important approach for pharmacological intervention in many diseases such as glaucoma, epilepsy, obesity, ... -
Anti-quorum sensing activity in Pseudomonas aeruginosa PA01 of benzimidazolium salts: electronic, spectral and structural investigations as theoretical approach
Önem, Ebru; Tüzün,Burak; Akkoç, Senem (taylor francis, 01.03.2021)Quorum sensing (QS) is a system used in the expression of virulence factors by many pathogenic bacteria, and blockage of the system is seen as a new and effective strategy in combating with resistant bacteria. The ... -
Applications of the Effectiveness of Corrosion Inhibitors with Computational Methods and Molecular Dynamics Simulation
erdoğan, şaban; Tüzün,Burak (26.07.2022)Many experts working in the field of corrosion work in laboratories experimentally with long-term procedures and high costs by making changes in the structures of new corrosion inhibitors or existing inhibitors. Advances ... -
Architectural View of Flexible Aliphatic –OH Group Coordinated Hemi‑Directed Pb(II)‑Salen Coordination Polymer: Synthesis, Crystal Structure, Spectroscopic Insights, Supramolecular Topographies, and DFT Perspective
Majumdar, Dhrubajyoti; Tüzün,Burak; Pal, Tapan Kumar; Das, Sourav; Bankura, Kalipada (27.01.2022, 27.01.2022)We serendipitously designed one novel 1D hetero-binuclear Zn(II)-Pb(II) coordination polymer, namely [(Zn)(Pb)(L)(η1– NCS)(η1–SCN)]n (1) from Salen ligand ( H3L) in the presence of NaSCN. The complex was structurally ... -
Biological effects and molecular docking studies of Catechin 5-O-gallate: antioxidant, anticholinergics, antiepileptic and antidiabetic potentials
Taslimi, Parham; Kocyigit, Umit M.; Tüzün,Burak; Kirici, Mahinur (Journal of Biomolecular Structure and Dynamics, 04.10.2020)Gallocatechin gallate is a form of catechin and an ester of gallocatechin and gallic acid. This is an epimer of the gallate epigallocatechin. In this study, the effect of this molecule, containing a biologically active ... -
Design, synthesis, characterization, biological evaluation, and molecular docking studies of novel 1,2-aminopropanthiols substituted derivatives as selective carbonic anhydrase, acetylcholinesterase and a-glycosidase enzymes inhibitors
Huseynova, Afat; Kaya, Ruya; Taslimi, Parham; Farzaliyev, Vagif; Mammadyarova, Xadija; Sujayev, Afsun; Tüzün,Burak; Kocyigit, Umit M.; Alwasel, Saleh; Gülçin, lhami (26.08.2020)In the article, various substituted derivatives of 1,2-aminopropanthiol (1a–g) have been prepared by a general and efficientmethod, in one-steps, starting fromavailable thiirane and aromatic amines (aniline, o-toluidine) ... -
Design, synthesis, characterization, biological evaluation, and molecular docking studies of novel 1,2-aminopropanthiols substituted derivatives as selective carbonic anhydrase, acetylcholinesterase and α-glycosidase enzymes inhibitors
Huseynova, Afat; Kaya, Ruya; Taslimi, Parham; Farzaliyev, Vagif; Mammadyarova, Xadija; Sujayev, Afsun; Tüzün,Burak; Kocyigit, Umit M.; Alwasel, Saleh; Gulçin, İlhami (27.08.2020)In the article, various substituted derivatives of 1,2-aminopropanthiol (1a–g) have been prepared by a general and efficientmethod, in one-steps, starting fromavailable thiirane and aromatic amines (aniline, o-toluidine) ... -
Development process for ecofriendly corrosion inhibitors
Rbaa, Mohamed; Galai, Mouhsine; Dagdag, Omar; Guo, Lei; Tüzün,Burak; Berdimurodov, Elyor; Zarrouk, Abdelkader; Lakhrissi, Brahim (26.07.2022)The metallic materials are main used materials, because, their physical properties, such as electrical conduction, thermal conduction, and mechanical performances. The steel based metallic materials are most common in ... -
Experimental and theoretical investigation of corrosion inhibition effect of two piperazine-based ligands on carbon steel in acidic media
Rezaeivala, Majid; Karimi, Saeid; Sayin, Koray; Tüzün,Burak (4.02.2022)hydroxyethyliminomethyl) phenyl)piperazine (1) or its reduced form, 1,4-bis(2-(2-hydroxyethylaminomethyl)phenyl)piperazine (2), as possible corrosion inhibitors, were compared to a solution containing no (1) or (2). The ... -
Quinoline-fused both non-peripheral and peripheral ZnII and MgII phthalocyanines: Anti-cholinesterase, anti- α-glucosidase, DNA nuclease, antioxidant activities, and in silico studies
Yalazan, Halise; Tüzün,Burak; Akkaya, Didem; Barut, Burak; Kantekin, Halit; Yıldırmıs, Sermet (08.04.2022)Quinoline-fused ZnII (ZnPcp/ZnPcnp) and MgII (MgPcp/MgPcnp) phthalocyanines with four 4-methylquinolin-2-ol (1) at non-peripheral or peripheral positions of the phthalocyanine core have been synthesized via cyclotetramerization ... -
Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3- mercapto-1,2,4-triazole
Shahzadi, Irum; Zahoor, Ameer Fawad; Tüzün,Burak; Mansha, Asim; Anjum, Muhammad Naveed; Rasul, Azhar; Irfan, Ali; Kotwica-Mojzych, Katarzyna; Mojzych, Mariusz (PLOS ONE, 15.12.2022)Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay. The synthesized series of azomethines exhibited ... -
Synthesis of (4R)-2-(3-hydroxyphenyl)thiazolidine 4-carboxylic acid substituted phthalocyanines: Anticancer activity on different cancer cell lines and molecular docking studies
Bilgiçli, Ahmet T.; Genc Bilgicli,Hayriye; Hepokur,Ceylan; Tüzün,Burak; Günsel, Armagan; Zengin, Mustafa; Yarasir,M. Nilüfer (2021)In this study, firstly, (4R)-2-(3-hydroxyphenyl)thiazolidine-4-carboxylic acid (1) and (4R)-2-(3-(3,4-dicyanophenoxy)phenyl)thiazolidine-4-carboxylic acid (2) were prepared. Then, the novel type metallophthalocyanines ... -
Synthesis, computational analyses, antibacterial and antibiofilm properties of nicotinamide derivatives
Taşkın Kafa, Ayşe Hümeyra; Tüzün, Gamze; Güney, Elif; Aslan, Rukiye; Sayın, Koray; Tüzün,Burak; Ataseven, Hilmi (Ağustos 20)Newly designed nicotinamide derivatives were synthesized and characterized using spectral techniques (IR, 1H-NMR, 13C-NMR, and MS). Moreover, these compounds are investigated computationally. B3LYP/6–31 + G(d,p) level is ... -
Unravelling the Synthetic Mimic, Spectroscopic Insights, and Supramolecular Crystal Engineering of an Innovative Heteronuclear Pb(II)‑Salen Cocrystal: An Integrated DFT, QTAIM/NCI Plot, NLO, Molecular Docking/PLIP, and Antibacterial Appraisal
Majumdar, Dhrubajyoti; Philip, Jessica Elizabeth; Tüzün,Burak; Frontera, A.; Gomila, Rosa M.; Roy, Sourav; Bankura, Kalipada (springer, 26.07.2022)Spontaneous self-assembly in the supramolecular entity is one of the enthralling synthetic routes. It produces disparate structure crystal complexes after selecting suitable M-L combinations in the pseudohalide sense. In ...
