Browsing by Author "Turan, Mustafa"
Now showing items 1-19 of 19
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Antitumoral effects of Allium sivasicum on breast cancer in vitro and in vivo
Tepe, Bektas; Tuncer, Ersin; Saraydin, Serpil Unver; Ozer, Hatice; Sen, Metin; Karadayi, Kursat; Inan, Deniz Sahin; Karadayi, Sule; Polat, Zubeyde; Akpulat, Askin; Duman, Mustafa; Koksal, Binnur; Turan, Mustafa (SPRINGER, 2013)This work aims to investigate the antiproliferative properties of Allium sivasicum (AS) on breast cancer. AS extracts were studied for cytotoxicity against the breast cancer cell lines. In vitro apoptosis studies of breast ... -
Antitumoral Effects of Melissa officinalis on Breast Cancer in Vitro and in Vivo
Saraydin, Serpil Unver; Tuncer, Ersin; Tepe, Bektas; Karadayi, Sule; Ozer, Hatice; Sen, Metin; Karadayi, Kursat; Inan, Deniz; Elagoz, Sahande; Polat, Zubeyde; Duman, Mustafa; Turan, Mustafa (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2012)Background: There is a long standing interest in the identification of medicinal plants and derived natural products for developing cancer therapeutics. Here we investigated the antiproliferative properties of Melissa ... -
Antitumoral effects of Salvia absconditiflora Greuter & Burdet syn. Salvia cryptantha Montbret & Aucher ex Benth. on Breast cancer
Ozer, Hatice; Altun, Ahmet; Saraydin, Serpil Unver; Soylu, Sinan; Goktas, Selcuk; Tuncer, Ersin; Inan, Deniz Sahin; Koksal, Binnur; Temiz, Tijen Kaya; Tepe, Bektas; Sen, Metin; Karadayi, Kursat; Turan, Mustafa (NATL INST SCIENCE COMMUNICATION-NISCAIR, 2013)This work aims to investigate the antiproliferative properties of Salvia cryptantha on breast cancer. Salvia cryptantha (SC) extracts were studied for cytotoxicity against the breast cancer cell lines. In-vitro apoptosis ... -
Comparative relaxant effects of YC-1 and DEA/NO on the sheep sphincter of Oddi
Bagcivan, Ihsan; Kaya, Tijen; Turan, Mustafa; Karadas, Baris; Sarac, Buelent; Duman, Mustafa (KARGER, 2006)Background/Aims: Nitric oxide (NO) is a major inhibitor in various parts of the gastrointestinal tract. This study was designed to compare the effects of YC-1, NO-independent soluble guanylate cyclase (sGC) activator, and ... -
Cytoreductive Surgery Followed by Hyperthermic Intraperitoneal Chemotherapy: Morbidity and Mortality Analysis of Our Patients
Karadayi, Kursat; Turan, Mustafa; Karadayi, Sule; Alagozlu, Hakan; Kilickap, Saadettin; Buyukcelik, Abdullah; Sarkis, Cihat; Yucel, Birsen; Boztosun, Abdullah; Cetin, Meral; Yilmaz, Abdulkerim; Yanik, Ali; Sen, Metin (ORTADOGU AD PRES & PUBL CO, 2012)Objective: The purpose of this study was to analyze the morbidity and mortality of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and early postoperative intraperitoneal chemotherapy ... -
Does hydatid disease have protective effects against lung cancer?
Karadayi, Sule; Arslan, Sulhattin; Sumer, Zeynep; Turan, Mustafa; Sumer, Haldun; Karadayi, Kursat (SPRINGER, 2013)We hypothesized that solid tumors rarely occur in patients with hydatid disease. We obtained the serum of 14 patients diagnosed with hydatid disease, the serum of 10 patients who did not have a history of hydatid disease, ... -
Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro
Sarac, Bulent; Durmus, Nedim; Altun, Ahmet; Turan, Mustafa; Kaya, Tijen; Sencan, Mehmet; Bagcivan, Ihsan (ELSEVIER SCIENCE BV, 2011)Background/Aims: According to recent studies, the endocannabinoid system plays an important role in both physiological and pathophysiological situations. The purpose of the present study was to investigate the effects of ... -
Effects of tyrosine kinase inhibitor E7080 and eNOS inhibitor L-NIO on colorectal cancer alone and in combination
Altun, Ahmet; Temiz, Tijen Kaya; Balci, Ezgi; Polat, Zubeyde Akin; Turan, Mustafa (SPRINGER, 2013)Objective: To investigate the effects of E7080 and N-5-(1-iminoethyl)-L-ornithine dihydrochloride (L-NIO) on colorectal cancer alone and in combination. Methods: HT29 colorectal cancer cell line from Sap Institute was used. ... -
Epigenetic Inactivation of Tumor Suppressor SFRP2 and Point Mutation in KRAS Proto-Oncogene in Fistula - Associated Mucinous Type Anal Adenocarcinoma: Report of Two Cases
Sen, Metin; Ozdemir, Oztuerk; Turan, Mustafa; Arici, Sema; Yildiz, Fazilet; Koksal, Binnur; Goze, Fahrettin (JAPAN SOC INTERNAL MEDICINE, 2010)The secreted frizzled-related proteins (SFRPs) genes are unmethylated in normal colorectal mucosa tissue but abberant methylation profiles can be detected in colorectal cancer (CRC), adenomas, and in aberrant crypt foci. ... -
Investigation of Relaxant Effects of New Agents Affecting Nitric Oxide/Cyclic Guanosine Monophosphate Pathway on Sheep Oddi Sphincter
Sarac, Bulent; Durmus, Nedim; Bagcivan, Ihsan; Altun, Ahmet; Turan, Mustafa; Sencan, Mehmet (LIPPINCOTT WILLIAMS & WILKINS, 2010)Objectives: Nitric oxide (NO) is a potent nonadrenergic, noncholinergic mediator of gastrointestinal smooth muscle. We aimed to investigate the effects of new NO/cyclic guanosine monophosphate (cGMP) pathway-affecting ... -
Investigation of relaxant effects of propofol on sheep sphincter of Oddi
Bagcivan, Ihsan; Gursoy, Sinan; Yildirim, M. Kemal; Temiz, Tijen Kaya; Yildirim, Sahin; Yilmaz, Abdulkerim; Turan, Mustafa (KARGER, 2007)Background/Aims: Intravenous anesthetics are often used for conscious sedation in endoscopic retrograde cholangio-pancreatography ( ERCP) and endoscopic sphincter of Oddi ( SO) manometry. This study was designed to investigate ... -
Investigation of the relaxant effects of pinacidil and Cromakalim on the sheep sphincter of Oddi
Bagcivan, Ihsan; Kaya, Tijen; Yildirim, M. Kemal; Turan, Mustafa (KARGER, 2006)Background/Aims: ATP-sensitive K+ (KATP) channels play an important role in the regulation of smooth muscle membrane potential. This study was designed to investigate the effects of pinacidil and cromakalim, KATP-sensitive ... -
KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients
Bagci, Binnur; Sari, Musa; Karadayi, Kursat; Turan, Mustafa; Ozdemir, Ozturk; Bagci, Gokhan (IOS PRESS, 2016)BACKGROUND: Colorectal cancer is a serious disease that causes significant morbidity and mortality in developed countries. Genetic changes, such as mutations in proto-oncogenes and DNA repair genes, and loss of function ... -
New partial splenectomy technique using radiofrequency ablation technology
Karadayi, Kursat; Turan, Mustafa; Sen, Metin (WILEY, 2010)The present case is of a patient undergoing radiofrequency-assisted partial splenectomy. A 48-year-old man was found to have a hydatic cyst in the superior pole of the spleen. A six in-line needle radiofrequency probe was ... -
A New Technique for Partial Spleenectomy With Radiofrequency Technology
Karadayi, Kursat; Turan, Mustafa; Sen, Metin (LIPPINCOTT WILLIAMS & WILKINS, 2011)The advantage of partial splenectomy is the preservation of its immunologic function. In this series, 8 patients underwent a spleen preservation procedure with radiofrequency. Four of the partial splenectomy procedures ... -
Small bowel tumors in emergency surgery
Turan, Mustafa; Karadayi, Kursat; Duman, Mustafa; Ozer, Hatice; Arici, Sema; Yildirir, Cihan; Kocak, Osman; Sen, Metin (TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2010)BACKGROUND The aim of the present study was to describe the clinical presentation, diagnostic work-up, surgical therapy, and prognosis of 13 patients with small bowel tumor admitted for surgical procedures in an emergency ... -
Spontaneous Enterocutaneous Fistula: A Rare Presentation of Incarcerated Femoral Hernia
Bostanci, Meric Emre; Ozel, Ilker; Bozkurt, Birkan; Soylu, Sinan; Turan, Mustafa (AVES, 2015)Although femoral hernias are less commonly seen compared with other types of hernias, they have an inversely proportional importance to its lower frequency because of its higher risk of strangulation, morbidity, and ... -
Synthesis, spectroscopic characterization, calculational studies and in vitro antitumoral activity of 4-(3-(1H-imidazol-1-yl)propyl)-(thiophen-2-ylmethyl)-1H-1,2,4-triazol-5(4H)-one
Suleymanoglu, Nevin; Ustabas, Resat; Alpaslan, Yelda Bingol; Unver, Yasemin; Turan, Mustafa; Sancak, Kemal (ELSEVIER SCIENCE BV, 2011)4-(3-(1H-imidazol-1-yl)propyl)-(thiophen-2-ylmethyl)-1H-1.2,4-triazol-5(4H)-one (IPTT), C13H15N5OS, was synthesized and characterized by C-13 NMR, H-1 NMR, IR and single-crystal X-ray diffraction. The structure of IPTT is ...
