Fakülteler: Recent submissions
Now showing items 1481-1500 of 2389
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MOLEKÜLER TÜR TANIMLAMASINDA BIR ARAÇ OLARAK DNA BARKODLAMA
(İksad Yayınevi, Aralık 202)Türlerin taksonomik tanımlamasında DNA kullanma kavramı ilk olarak Hebert ve Gregory tarafından önerilmiştir (P. D. Hebert ve ark., 2003). DNA barkodlama kavramı, türleri birbirinden ayırmak için kullanılabilen "küçük ... -
Kolorektal kanser kök hücre izolasyonu, tanımlanması ve kültürü.
(İksad Yayınevi, Ekim 2022)Kolorektal kanser (KRK), kanser ölümlerinin üçüncü nedeni olarak bilinir ve dünya çapında en yaygın malignite türleri arasındadır (Inamura, 2018). Bu hastalık için farklı tedavi yöntemleri ile çeşitli cerrahi ve medikal ... -
A comprehensive and current review on the role of flavonoids in lung cancer–Experimental and theoretical approaches
(17 Şubat )Background: It is well-known that flavonoids, which can be easily obtained from many fruits and vegetables are widely preferred in the treatment of some important diseases. Some researchers noted that these chemical compounds ... -
CAENORHABDITIS ELEGANS MODEL ORGANİZMASINDA TRANSKRİPTOM VE METABOLOM ANALİZLERİ
(Serüven yayınevi, Aralık 202)Metabonomi veya metabolomik, spektrometri ve genomik araştırmaları sonrası bu teknolojiler ile geliştirilen yeni bir "omik" disiplini olup, genellikle, canlı sistemlerdeki tüm metabolitlerin ve eksojen uyaranlara, genetik ... -
Anti-kanser ilaç keşfi için bir model olarak Caenorhabditis elegans
(Livre de Lyon, Ekim 2022)1963'te Sydney Brenner, Tıbbi Araştırma Konseyi'nin Moleküler Biyoloji Laboratuvarı (LMB) başkanı Max Perutz'a, “moleküler biyolojinin klasik sorunlarının ya çözüldüğü ya da önümüzdeki on yıl içinde çözüleceği” konusundaki ... -
Optimization of magnetic ionic based dispersive liquid-liquid microextraction of cadmium in water and food samples using experimental design prior to flame atomic absorption spectrophotometry
(2022)A magnetic ionic based dispersive liquid liquid microextraction (MIL-DLLME) procedure was optimized for the analysis and extraction of cadmium in water and food samples by flame atomic absorption spectrophotometry (FAAS). ... -
Magnetic solid-phase extraction coupled to high-performance liquid chromatography (HPLC)-diode array detection method has been developed for the sensitive analysis of Anastrozole (ANA) and Letrozole (LET) in human urine samples. Characterization studies of the newly synthesized material (Fe3O4@TEPA) were carried out by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction, Raman spectroscopy, and scanning electron microscope techniques. The method has provided linearity for both the analytes (r2 > 0.9900) in the range of 4.00–160.00 ng mL−1. The limit of detections for ANA and LET was found to be 1.14 and 1.26 ng mL−1, respectively. The limit of quantification for ANA and LET was obtained 3.78 and 3.86 ng mL−1, respectively. The new method was simple, convenient, fast, and suitable for the direct analysis of ANA and LET in urine samples. Finally, the developed method was applied to the spiked human urine samples to test accuracy and repeatability. Recovery values for each of the molecules were calculated in the range of 93.4–108.0% (n = 3) at two concentration levels, while % RSDs were lower than 6.2%. Graphical abstract
(Elsevier, 15.04.2022)A new Polyacrylamide (PAA)-Vermiculite (V) composite was synthesized and characterized with the help of FTIR, SEM, and PZC analyses. The effects of ion concentration, pH and ionic strength parameters to adsorption process ... -
Güncel Uygulanan Kanser Tedavi Yöntemleri
(Bilgin Kültür Sanat Yayınları, 25.12.2022)Modern tıp her ne kadar ilerlemiş olsa da kanser için hastalık görülmeden önce ortaya çıkarılması ve erken safhada önlenmesi hala çok önemlidir. Kansere karşı koruyucu olarak; en büyük nedenlerinden biri olan sigara ve ... -
Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects
(Medicinal Chemistry Research, 08.08.2022)In this study, eleven new compounds with a series of benzimidazole-1,3,4-oxadiazole derivatives structures were synthesized and evaluated for their human (h) carbonic anhydrase inhibitory activities against two isoforms ... -
Benzimidazole-hydrazone derivatives: Synthesis, in vitro anticancer, antimicrobial, antioxidant activities, in silico DFT and ADMET studies
(Elsevier, 14.08.2022)Based on the biologically active heterocycle compounds, a series of new benzimidazole-hydrazone deriva- tives ( 3a-3j ) were synthesized, starting from 4-(6-chloro-1 H -benzimidazol-2-yl) benzohydrazide. The syn- thesized ... -
Synthesis, and docking studies of novel tetrazole S-alkyl derivatives as antimicrobial agents
(Taylor & Francis, 01.09.2022)A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC 22019) and ... -
Spectra and fine spectra of the generalized upper difference operator with triple repetition ∆_3^ab on the Hahn sequence space
(De Gruyter, 2022)The goal of this paper is to obtain the spectra and ne spectra of the matrix D_3âb on the Hahn space. Also, we explore some ideas of how to study the problem for a general form of the matrix, namely, the matrix D_3âb where ... -
Synthesis, Molecular Docking, Dynamics, Quantum-Chemical Computation, and Antimicrobial Activity Studies of Some New Benzimidazole−Thiadiazole Hybrids
(ACS, 09.11.2022)In this study, some new compounds, which are 2aminothiadiazole derivatives linked by a phenyl bridge to the 2position of the benzimidazole ring, were designed and synthesized as antimicrobial agents. The structures of ... -
Fen Bilimleri Eğitiminde Mobil Teknoloji Destekli Uygulamalar
(Gece Kitaplığı Yayınevi, Haziran 20)Günümüzde teknoloji, hayatı daha kolay ve verimli hale getirmede en önemli rolü oynamaktadır. Akıllı telefonların uygun fiyatlarla bulunması, iletişim, seyahat, eğlence, üretkenlik ve öğrenme gibi hayatın çeşitli yönlerine ... -
Mobil Uygulamalar ve Yabancı Dil Öğrenimi, Öğretim Teknolojileri
(EĞİTEN KİTAP, 2022)Mobil teknolojilere sahip cihazların yaygınlaşmasıyla birlikte, insanların internete her yerden ve her zaman (Zhao & Liu, 2019) erişebilmelerine olanak sağlanması internet, hayatın her alanında önemli hale getirerek ve ... -
Evaluation of the effects of newly synthesized metallophthalocyanines on breast cancer cell lines with photodynamic therapy
(Royal Society of Chemistry, 21.09.2022)In this study, the new phthalonitrile derivative 3-(4-(3-oxobutyl)phenoxy)phthalonitrile (1) and its nonperipheral metallophthalocyanine derivatives [zinc (2), copper (3), cobalt (4), manganese (5), gallium (6), and ... -
Synthesized of poly(vinyl benzyl dithiocarbonate-dimethyl amino ethyl methacrylate) block copolymer as adsorbent for the vortex-assisted dispersive solid phase microextraction of patulin from apple products and dried fruits
(Elsevier, 2022)A new and novel poly(vinyl benzyl dithiocarbonate-dimethyl amino ethyl methacrylate) block copolymer (Pvb-DMA-Xa) as adsorbent was synthesized for the vortex-assisted dispersive solid phase microextraction (VADSPME) of ... -
Artificial-intelligence-supported shell-model calculations for light Sn isotopes
(American Physical Society, 11/04/2022)The region around the doubly magic nuclide 100 Sn is very interesting for nuclear physics studies in terms of structure, reaction, and nuclear astrophysics. The main ingredients in nuclear structure studies using the ... -
Synthesis of polystyrene-polyricinoleic acid copolymer containing silver nano particles for dispersive solid phase microextraction of molybdenum in water and food samples
(Elsevier, 2022)Polystyrene-polyricinoleic acid copolymer containing silver nano particles (AgPSrici) was synthesized and used in separation of molybdenum from different aqueous and foodstuff samples during a dispersive-μ-solid phase ... -
Neural network estimations of annealed and non-annealed Schottky diode characteristics at wide temperatures range
(Elsevier, 15/06/2022)In this study, Artificial Neural Network (ANN) model has been proposed to characterize the annealed and the non-annealed Schottky diode from experimental data. The experimental current values of Ni/n-type 6H–SiC Schottky ...