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Investigating the effects of the Rho-kinase enzyme inhibitors AS1892802 and fasudil hydrochloride on the contractions of isolated pregnant rat myometrium
(ELSEVIER SCIENCE BV, 2016)
Objectives: Rho-kinases (ROCKs), are one of the dynamic structures of the actin cytoskeleton and they mediate different biological processes, including regulation of calcium sensitivity of smooth muscle contraction. The ...
Sensitive determination of Fluoxetine and Citalopram antidepressants in urine and wastewater samples by liquid chromatography coupled with photodiode array detector
(02.05.2021)
A new analyte separation and preconcentration method for the trace determination of antidepressant drugs, Fluoxetine (FLU) and Citalopram (CIT) in urine and wastewaters, was developed based on HPLC-DAD analysis after ...
Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
(ELSEVİER, 2021)
In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes
which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new
compounds were ...
Michael/Michael Addition Cascade of 2-Benzylidene-1- indanones with Chalcones: Synthesis and Biological Evaluations of Novel Polycyclic Compounds
(WİLLEY ONLİNE LİBRARY, 2021)
A series of novel racemic 2-aryloyl-1,3-diaryl-2,3,3a,8a-tetrahydrocyclopenta[
a]inden-8(1H)-one derivatives were synthesized
from KOtBu mediated Michael/Michael addition reaction of 2-
benzylidene-1-indanones with ...
Pharmacokinetic Profiles of Metamizole Metabolites after Intramuscular and Intravenous Administration in Healthy Arabian Horses
(2021)
Metamizole sodium (MT) is an analgesic and antipyretic drug molecule used in humans,
horses, cattle, swine, and dogs. Metamizole rapidly hydrolyzes and turns into methyl amino antipyrine (MAA), an active primary metabolite ...
Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes†
(The Royal Society, 2021)
Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host
cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals.
Inhibition ...
Investigation of the Antimicrobial Agent Potential of 1,5-diketon Derivatives
(2021)
In this study 1,5-diketones were synthesized by adding of cyclohexzanone to five differtent calcone derivatives (1a-e) via di-1,4-Michael addition reaction. As a result the compounds with the best activity were 3a, 3b and ...
Ionic Liquids in Analytical Chemistry: Applications and Recent Trends
(03.07.2021)
Background: Ionic liquids (ILs) are a unique class of compounds consisting exclusively of cations and anions that possess distinctive properties such as low volatility, high thermal stability, miscibility with water and ...
Determination of chloramphenicol and tetracycline residues in milk samples by means of nanofiber coated magnetic particles prior to high-performance liquid chromatography-diode array detection
(Elsevier, 08.03.2021)
A magnetic solid phase extraction (MSPE) coupled with high-performance liquid chromatography-diode array
detection (HPLC-DAD) methodology was developed for the determination of chloramphenicol (CP) and tetracycline
(TET) ...
Fabric-Phase Sorptive Membrane Array As a Noninvasive In Vivo Sampling Device For Human Exposure To Different Compounds
(ACs, 20.01.2021)
This study introduces an innovative device for the
noninvasive sampling and chromatographic analysis of different
compounds present in exhaled breath aerosol (EBA). The new
sampling device, especially in light of the ...