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Evaluation of Endothelium Functions by Flow-mediated Dilatation in Pediatric Patients With Crimean-Congo Hemorrhagic Fever

Karapinar, Hekim; Kaya, Ali; Uysal, Elif Bilge; Kucukdurmaz, Zekeriya; Deveci, Koksal; Guven, Ahmet Sami; Sancakdar, Enver; Yilmaz, Ahmet (LIPPINCOTT WILLIAMS & WILKINS, 2015)

Background: Crimean-Congo hemorrhagic fever (CCHF) is a systemic viral disease that also affects the endothelium. Thrombocytopenia and hemorrhage are seen in this disease. But, the cause of thrombocytopenia is not clear. ...

Alterations of serum brain type natriuretic peptide (BNP) in patients with Crimean-Congo hemorrhagic fever

Uysal, Elif Bilge; Sancakdar, Enver; Seker, Ayse; Deveci, Koksal; Tuzcu, Nevin; Karapinar, Hekim (E-CENTURY PUBLISHING CORP, 2015)

Background: Crimean-Congo hemorrhagic fever (CCHF) is known to be associated with cardiac damage. Brain type natriuretic peptide (BNP) is secreted from stressed myocardium. Objectives: This study investigated that BNP ...

Important of Angiopoietic System in Evaluation of Endothelial Damage in Children with Crimean-Congo Hemorrhagic Fever

Sancakdar, Enver; Guven, Ahmet S.; Uysal, Elif B.; Deveci, Koksal; Gulturk, Esra (LIPPINCOTT WILLIAMS & WILKINS, 2015)

Background: Crimean-Congo hemorrhagic fever (CCHF) causes endothelial activation and dysfunction by affecting the endothelium directly or indirectly. In maintaining the vascular integrity, vascular endothelial growth factor ...

Toll-like Receptor 7 Gln11Leu, c.4-151A/G, and+1817G/T Polymorphisms in Crimean Congo Hemorrhagic Fever

Arslan, Serdal; Engin, Aynur; Ozbilum, Nil; Bakir, Mehmet (WILEY, 2015)

Crimean-Congo hemorrhagic fever (CCHF) is a viral zoonosis. Toll-like receptors (TLRs) initiate signaling cascades leading to the activation of the innate immune system following CCHF infection. In this study, TLR7 (Gln11Leu, ...

Vitamin D status in children with Crimean-Congo hemorrhagic fever

Uysal, E. B.; Tuzcu, N.; Sancakdar, E.; Guven, A. S.; Akkar, I.; Deveci, K.; Kaya, A. (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2015)

Background & objectives: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease, causing severe viral hemorrhagic fever outbreaks. This study aimed at determining the serum vitamin D levels and investigated ...

Evaluation of Serum Perforin, Caspase-3, sFasL and M-30 Levels as Apoptotic Markers in Children With Crimean-Congo Hemorrhagic Fever

Guven, Ahmet S.; Sancakdar, Enver; Uysal, Elif B.; Kaya, Ali; Oflaz, Mehmet B.; Karapinar, Hekim; Bolat, Fatih; Tuzcu, Nevin; Deveci, Koksal; Cevit, Omer; Icagasioglu, Fusun D. (LIPPINCOTT WILLIAMS & WILKINS, 2015)

Background: Apoptosis is a main regulator in responses of cellular immunity throughout systemic viral infections. Perforin, soluble Fas ligand, caspase-3 and caspase-cleaved cytokeratin-18 (M-30) are mediators of apoptosis. ...

Elevated chemokine levels during adult but not pediatric Crimean-Congo hemorrhagic fever

Arasli, Mehmet; Ozsurekci, Yasemin; Elaldi, Nazif; McAuley, Alexander J.; Oncel, Eda Karadag; Tekin, Ishak Ozel; Gozel, Mustafa Gokhan; Kaya, Ali; Icagasioglu, Fusun Dilara; Caglayik, Dilek Yagci; Korukluoglu, Gulay; Kokturk, Furuzan; Bakir, Mehmet; Bente, Dennis A.; Ceyhan, Mehmet (ELSEVIER SCIENCE BV, 2015)

Background: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis. Clinical reports indicate the severity of CCHF is milder in children than adults. The chemokines are important chemoattractant mediators ...