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EVALUATION OF RESPIRATORY FINDINGS IN CRIMEAN-CONGO HEMORRHAGIC FEVER 

Dogan, Omer Tamer; Engin, Aynur; Salk, Ismail; Epozturk, Kursat; Eren, Sevki Hakan; Elaldi, Nazif; Bakir, Mehmet; Dokmetas, Ilyas; Akkurt, Ibrahim (SOUTHEAST ASIAN MINISTERS EDUC ORGANIZATION, 2011)
Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic disease with a high mortality rate causing viral hemorrhagic fever. We studies the respiratory system findings, demographics, clinical and laboratory findings of patients ...

Relationship of plasma cell-free DNA level with mortality and prognosis in patients with Crimean-Congo hemorrhagic fever 

Bakir, Mehmet; Engin, Aynur; Kuskucu, Mert Ahmet; Bakir, Sevtap; Gundag, Omur; Midilli, Kenan (WILEY, 2016)
Crimean-Congo hemorrhagic fever (CCHF) is a viral infection. Circulating plasma cell-free DNA (pcf-DNA) is a novel marker indicating cellular damage. So far, the role of pcf-DNA did not investigate in CCHF patients. In the ...

Apoptosis and its relation with clinical course in patients with Crimean-Congo hemorrhagic fever 

Engin, Aynur; Aydin, Huseyin; Cinar, Ziynet; Buyuktuna, Seyit Ali; Bakir, Mehmet (WILEY, 2019)
Crimean-Congo hemorrhagic fever (CCHF) is a tick-mediated viral infection. Patients with CCHF may show various clinical presentations. The cause of this difference in the clinical course is not completely understood. ...

A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever 

Bakir, Mehmet; Engin, Aynur; Gozel, Mustafa Gokhan; Elaldi, Nazif; Kilickap, Saadettin; Cinar, Ziynet (MALARIA RESEARCH CENTRE, INDIAN COUNCIL MEDICAL RESEARCH-ICMR, 2012)
Background & objectives: We have established a severity grading score (SOS) system for predicting the fatality :in Crimean-Congo hemorrhagic fever (CCHF) for the first time. Methods: This SOS has been set up by using several ...

Does electrocardiography at admission predict outcome in Crimean-Congo hemorrhagic fever? 

Yilmaz, Mehmet Birhan; Engin, Aynur; Bektasoglu, Gokhan; Zorlu, Ali; Ege, Meltem Refiker; Bakir, Mehmet; Dokmetas, Ilyas (MALARIA RESEARCH CENTRE, INDIAN COUNCIL MEDICAL RESEARCH-ICMR, 2011)
Background & objectives: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with considerable mortality. Despite increasing knowledge about hemorrhagic fever viruses, the pathogenesis of Crimean-Congo ...

Evaluation of the relationship between serum levels of VEGF and sVEGFR1 with mortality and prognosis in patients with Crimean-Congo hemorrhagic fever 

Bakir, Mehmet; Bakir, Sevtap; Sari, Ismail; Celik, Veysel Kenan; Gozel, Mustafa Gokhan; Engin, Aynur (WILEY-BLACKWELL, 2013)
The most accepted view to explaining the pathogenesis of Crimean-Congo hemorrhagic fever (CCHF) is endothelial damage. This study was conducted in a University hospital to investigate the serum levels and prognostic ...

Recommended precaution procedures protect healthcare workers from Crimean-Congo hemorrhagic fever virus 

Gozel, Mustafa Gokhan; Dokmetas, Ilyas; Oztop, Atifet Yasemin; Engin, Aynur; Elaldi, Nazif; Bakir, Mehmet (ELSEVIER SCI LTD, 2013)
Objectives: The Crimean-Congo hemorrhagic fever (CCHF) virus can spread from person to person and may cause nosocomial outbreaks among healthcare workers (HCWs). The US Centers for Disease Control and Prevention have ...

Toll-like Receptor 7 Gln11Leu, c.4-151A/G, and+1817G/T Polymorphisms in Crimean Congo Hemorrhagic Fever 

Arslan, Serdal; Engin, Aynur; Ozbilum, Nil; Bakir, Mehmet (WILEY, 2015)
Crimean-Congo hemorrhagic fever (CCHF) is a viral zoonosis. Toll-like receptors (TLRs) initiate signaling cascades leading to the activation of the innate immune system following CCHF infection. In this study, TLR7 (Gln11Leu, ...

Elevated chemokine levels during adult but not pediatric Crimean-Congo hemorrhagic fever 

Arasli, Mehmet; Ozsurekci, Yasemin; Elaldi, Nazif; McAuley, Alexander J.; Oncel, Eda Karadag; Tekin, Ishak Ozel; Gozel, Mustafa Gokhan; Kaya, Ali; Icagasioglu, Fusun Dilara; Caglayik, Dilek Yagci; Korukluoglu, Gulay; Kokturk, Furuzan; Bakir, Mehmet; Bente, Dennis A.; Ceyhan, Mehmet (ELSEVIER SCIENCE BV, 2015)
Background: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis. Clinical reports indicate the severity of CCHF is milder in children than adults. The chemokines are important chemoattractant mediators ...



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