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Substitution of the conserved cysteine with glycine (Cys82Gly) of Agmenellum quadruplicatum methylase Aqul (M. Aqul) is not cytotoxic to E. coli
Cytosine 5 DNA methyltransferases share ten conserved motifs. Motif IV contains an absolutely conserved proline-cysteine dipeptide. The cysteine residue of this motif is involved in catalysis by forming a covalent bond ...