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Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure

Mebazaa, Alexandre; Laterre, Pierre Francois; Russell, James A.; Bergmann, Andreas; Gattinoni, Luciano; Gayat, Etienne; Harhay, Michael O.; Hartmann, Oliver; Hein, Frauke; Kjolbye, Anne Louise; Legrand, Matthieu; Lewis, Roger J.; Marshall, John C.; Marx, Gernot; Radermacher, Peter; Schroedter, Mathias; Scigalla, Paul; Stough, Wendy Gattis; Struck, Joachim; Van den Berghe, Greet; Yilmaz, Mehmet Birhan; Angus, Derek C. (BMC, 2016)

Substantial attention and resources have been directed to improving outcomes of patients with critical illnesses, in particular sepsis, but all recent clinical trials testing various interventions or strategies have failed ...

Data on prevalence of metabolic syndrome in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors

Abaci, Adnan; Kilickap, Mustafa; Goksuluk, Huseyin; Karaaslan, Doruk; Barcin, Cem; Kayikcioglu, Meral; Ozer, Necla; Yilmaz, Mehmet Birhan; Sahin, Mahmut; Tokgozoglu, Lale (TURKISH SOC CARDIOLOGY, 2018)

Objective: The incidence of metabolic syndrome varies greatly in developed and developing countries. In the last 10 to 15 years, important studies have been performed examining the incidence of metabolic syndrome in Turkey. ...

Data on prevalence of hypertension and blood pressure in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors

Kilickap, Mustafa; Barcin, Cem; Goksuluk, Huseyin; Karaaslan, Doruk; Ozer, Necla; Kayikcioglu, Meral; Ural, Dilek; Yilmaz, Mehmet Birhan; Abaci, Adnan; Arici, Mustafa; Altun, Bulent; Tokgozoglu, Lale; Sahin, Mahmut (TURKISH SOC CARDIOLOGY, 2018)

Objective: Cardiovascular risc factors may show significant changes over the years. A systematic review and meta-analysis of epidemiological studies conducted in Turkey was performed to assess the latest profile and temporal ...

Cancer antigen-125 and risk of atrial fibrillation: a systematic review and meta-analysis

Cheung, Angel; Gong, Mengqi; Bellanti, Roberto; Ali-Hasan-Al-Saegh, Sadeq; Li, Guangping; Roig, Eulalia; Nunez, Julio; Stamos, Thomas D.; Yilmaz, Mehmet Birhan; Hakki, Kaya; Wu, William K. K.; Wong, Sunny Hei; Wong, Wing Tak; Bazoukis, George; Lampropoulos, Konstantinos; Tse, Lah Ah; Zhao, Jichao; Lip, Gregory Y. H.; Baranchuk, Adrian; Wong, Martin C. S.; Liu, Tong; Tse, Gary (BMJ PUBLISHING GROUP, 2018)

Background Cancer antigen-125 (Ca-125) is traditionally recognised as a tumour marker and its role in cardiovascular diseases has been studied only in recent years. Whether Ca-125 is elevated in patients with atrial ...

Data on smoking in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors

Ozer, Necla; Kilickap, Mustafa; Tokgozoglu, Lale; Goksuluk, Huseyin; Karaaslan, Doruk; Kayikcioglu, Meral; Yilmaz, Mehmet Birhan; Barcin, Cem; Abaci, Adnan; Sahin, Mahmut (TURKISH SOC CARDIOLOGY, 2018)

Objective: Smoking is one of the most important public health problems and preventable causes of mortality in Turkey. Major healthcare policies have been implemented to combat this problem over the past 10 years. The aim ...

Iron deficiency and anemia in heart failure

Cavusoglu, Yuksel; Altay, Hakan; Cetiner, Mustafa; Guvenc, Tolga Sinan; Temizhan, Ahmet; Ural, Dilek; Yesilbursa, Dilek; Yildirim, Nesligul; Yilmaz, Mehmet Birhan (TURKISH SOC CARDIOLOGY, 2017)

Heart failure is an important community health problem. Prevalence and incidence of heart failure have continued to rise over the years. Despite recent advances in heart failure therapy, prognosis is still poor, rehospitalization ...

Tumour biomarkers in heart failure: is there a role for CA-125?

Yilmaz, Mehmet Birhan; Nikolaou, Maria; Solal, Alain Cohen (WILEY, 2011)

Tumour markers are used for the screening, diagnosis, and stratification of cancer disease. Recently, the potential role of some tumour markers has also been explored in the context of heart failure. These include CA-125, ...

Highlights from ACC.17 scientific sessions

Yilmaz, Mehmet Birhan; Sahin, Mahmut (TURKISH SOC CARDIOLOGY, 2017)

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Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

Harjola, Veli-Pekka; Mullens, Wilfried; Banaszewski, Marek; Bauersachs, Johann; Brunner-La Rocca, Hans-Peter; Chioncel, Ovidiu; Collins, Sean P.; Doehner, Wolfram; Filippatos, Gerasimos S.; Flammer, Andreas J.; Fuhrmann, Valentin; Lainscak, Mitja; Lassus, Johan; Legrand, Matthieu; Masip, Josep; Mueller, Christian; Papp, Zoltan; Parissis, John; Platz, Elke; Rudiger, Alain; Ruschitzka, Frank; Schaefer, Andreas; Seferovic, Petar M.; Skouri, Hadi; Yilmaz, Mehmet Birhan; Mebazaa, Alexandre (WILEY, 2017)

Organ injury and impairment are commonly observed in patients with acute heart failure (AHF), and congestion is an essential pathophysiological mechanism of impaired organ function. Congestion is the predominant clinical ...

Data on prevalence of dyslipidemia and lipid values in Turkey: Systematic review and meta-analysis of epidemiological studies on cardiovascular risk factors

Kayikcioglu, Meral; Tokgozoglu, Lale; Kilickap, Mustafa; Goksuluk, Huseyin; Karaaslan, Doruk; Ozer, Necla; Abaci, Adnan; Yilmaz, Mehmet Birhan; Barcin, Cem; Ates, Kenan; Bayram, Fahri; Sahin, Mahmut; Ural, Dilek (TURKISH SOC CARDIOLOGY, 2018)

Objective: Dyslipidemias, primarily hypercholesterolemia, are independent and strong predictors of cardiovascular (CV) events. The frequency of dyslipidemia is very important in terms of determining CV prevention policies. ...