Browsing by Author "Altun, Ahmet"
Now showing items 1-20 of 29
-
Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis
Koyluogu, Gokhan; Bageivan, Ihsan; Karadas, Baris; Guney, Cengiz; Durmus, Nedim; Altun, Ahmet; Kaya, Tijen (ELSEVIER SCIENCE BV, 2008)The aim of this study was to investigate the effects of peritonitis on spontaneous contractions of ileum and jejunum smooth muscles isolated from rats. Peritonitis was induced by cecal ligation and puncture in 8 rats. ... -
Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis
Aydin, Cengiz; Bagcivan, Ihsan; Gursoy, Sinan; Altun, Ahmet; Topcu, Omer; Koyuncu, Ayhan (W J G PRESS, 2009)AIM: To investigate in vitro effects of propofol, midazolam and dexmedetomidine, which are commonly used anaesthesic or sedatives, on spontaneous contractions of the ileum both in normal rats and those exposed to hyperdynamic ... -
Antiangiogenic activities of bemiparin sodium, enoxaparin sodium, nadroparin calcium and tinzaparin sodium
Dogan, Omer Tamer; Polat, Zubeyde Akin; Karahan, Oguz; Epozturk, Kursat; Altun, Ahmet; Akkurt, Ibrahim; Cetin, Ali (PERGAMON-ELSEVIER SCIENCE LTD, 2011)Introduction: The low-molecular-weight heparins have been demonstrated to have antiangiogenic effects in various assays. We aimed to demonstrate and compare the antiangiogenic effects of four types of commercially available ... -
The antiangiogenic effects of levosimendan in a CAM assay
Katrancioglu, Nurkay; Karahan, Oguz; Kilic, Ahmet Turhan; Altun, Ahmet; Katrancioglu, Ozgur; Polat, Zubeyde Akin (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2012)Background: There is a physiological balance between the stimulatory and inhibitory signals for blood vessel growth. In many symptomatic patients with peripheral artery disease, coronary artery disease, and ischemic chronic ... -
Anticancer Effect of COX-2 Inhibitor DuP-697 Alone and in Combination with Tyrosine Kinase Inhibitor (E7080) on Colon Cancer Cell Lines
Altun, Ahmet; Turgut, Nergiz Hacer; Kaya, Tijen Temiz (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)Colorectal cancer remains one of the most common types of cancer and a leading cause of cancer death worldwide. In this study, we aimed to investigate effects of DuP-697, an irreversible selective inhibitor of COX-2 on ... -
Antitumoral effects of Salvia absconditiflora Greuter & Burdet syn. Salvia cryptantha Montbret & Aucher ex Benth. on Breast cancer
Ozer, Hatice; Altun, Ahmet; Saraydin, Serpil Unver; Soylu, Sinan; Goktas, Selcuk; Tuncer, Ersin; Inan, Deniz Sahin; Koksal, Binnur; Temiz, Tijen Kaya; Tepe, Bektas; Sen, Metin; Karadayi, Kursat; Turan, Mustafa (NATL INST SCIENCE COMMUNICATION-NISCAIR, 2013)This work aims to investigate the antiproliferative properties of Salvia cryptantha on breast cancer. Salvia cryptantha (SC) extracts were studied for cytotoxicity against the breast cancer cell lines. In-vitro apoptosis ... -
Attenuation of morphine antinociceptive tolerance by cannabinoid CB1 and CB2 receptor antagonists
Altun, Ahmet; Yildirim, Kemal; Ozdemir, Ercan; Bagcivan, Ihsan; Gursoy, Sinan; Durmus, Nedim (SPRINGER JAPAN KK, 2015)Cannabinoid CB1 and CB2 receptor antagonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The aim of this study was to investigate the ... -
Comparison of In Vitro Effects of Opioid Analgesics on Spontaneous Proximal and Distal Colon Contractions in Healthy Rats and Rats with Peritonitis
Ersan, Idris; Gursoy, Sinan; Avci, Onur; Altun, Ahmet; Bagcivan, Ihsan; Duger, Cevdet; Kol, Iclal Ozdemir; Kaygusuz, Kenan; Mimaroglu, Mehmet Caner (AVES, 2018)Objective: The goal of this study was to investigate and compare the effects of opioids on proximal and distal colon contractions in normal rats and rats with peritonitis, with and without the presence of naloxone in the ... -
Comparison of the antiangiogenic effects of heparin sodium, enoxaparin sodium, and tinzaparin sodium by using chorioallantoic membrane assay
Katrancioglu, Nurkay; Karahan, Oguz; Kilic, Ahmet Turhan; Altun, Ahmet; Katrancioglu, Ozgur; Polat, Zubeyde Akin (LIPPINCOTT WILLIAMS & WILKINS, 2012)Unfractionated heparin (UFH) and low molecular weight heparins have been used as anticoagulation agents in cardiovascular clinics for decades. However, these molecules also have potent antiangiogenic effects. Whereas, ... -
Cytotoxicity of bracket identification dyes
Celebi, Fatih; Altun, Ahmet; Bicakci, Ali Altug (E H ANGLE EDUCATION RESEARCH FOUNDATION, INC, 2019)Objectives: To investigate the potential cytotoxicity of the bracket identification dyes commonly used in orthodontic fixed appliances. Materials and Methods: Six bracket brands representing the market in various aspects ... -
The effect of intravenous pamidronate treatment for type i osteogenesis imperfecta patients have on their bone mineral density, fracture rate, and mobility
Oztemur, Zekeriya; Ozturk, Hayati; Circi, Esra; Bulut, Okay; Uner, Serdar; Altun, Ahmet; Tezeren, Gunduz (DRUNPP-SARAJEVO, 2012)Objective: Osteogenesis imperfecta (OI) is a genetic disorder caused by the mutation in encoding collagen type I, and characterised by fragile bone and reduced bone mineral density. The purpose of this study was to analyse ... -
Effects and Selectivity of CL 316243, Beta-3-Adrenoceptor Agonist, in Term-Pregnant Rat Myometrium
Kaya, Tijen; Karadas, Baris; Altun, Ahmet; Sarac, Ikram; Bagcivan, Ihsan (KARGER, 2012)Background/Aims: Recent evidence supports a predominant role of beta(3)-adrenoceptors at the end of pregnancy in myometrium. This study was designed to characterize the pharmacology of the selective beta(3)-adrenoceptor ... -
Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats
Gursoy, Sinan; Ozdemir, Ercan; Bagcivan, Ihsan; Altun, Ahmet; Durmus, Nedim (TAYLOR & FRANCIS LTD, 2011)Background. Alpha 2 (alpha(2))-adrenoceptor agonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The purpose of this study was to investigate ... -
Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro
Sarac, Bulent; Durmus, Nedim; Altun, Ahmet; Turan, Mustafa; Kaya, Tijen; Sencan, Mehmet; Bagcivan, Ihsan (ELSEVIER SCIENCE BV, 2011)Background/Aims: According to recent studies, the endocannabinoid system plays an important role in both physiological and pathophysiological situations. The purpose of the present study was to investigate the effects of ... -
The effects of endocannabinoid receptor agonist anandamide and antagonist rimonabant on opioid analgesia and tolerance in rats
Altun, Ahmet; Ozdemir, Ercan; Yildirim, Kemal; Gursoy, Sinan; Durmus, Nedim; Bagcivan, Ihsan (GENERAL PHYSIOL AND BIOPHYSICS, 2015)The role of the cannabinoid (CB) system in the tolerance to analgesic effect of opioid remains obscure. The aim of the present study was to evaluate the effects of the endocannabinoid nonselective receptor agonist anandamide ... -
Effects of Proton Pump Inhibitors and H-2 Receptor Antagonists on the Ileum Motility
Kurt, Atilla; Altun, Ahmet; Bagcivan, Ihsan; Koyuncu, Ayhan; Topcu, Omer; Aydin, Cengiz; Kaya, Tijen (HINDAWI PUBLISHING CORPORATION, 2011)Objectives. To investigate the effects of proton pump inhibitors (PPIs) and H-2 receptor antagonists on ileum motility in rats with peritonitis and compare changes with control group rats. Methods. Peritonitis was induced ... -
Effects of tyrosine kinase inhibitor E7080 and eNOS inhibitor L-NIO on colorectal cancer alone and in combination
Altun, Ahmet; Temiz, Tijen Kaya; Balci, Ezgi; Polat, Zubeyde Akin; Turan, Mustafa (SPRINGER, 2013)Objective: To investigate the effects of E7080 and N-5-(1-iminoethyl)-L-ornithine dihydrochloride (L-NIO) on colorectal cancer alone and in combination. Methods: HT29 colorectal cancer cell line from Sap Institute was used. ... -
Evaluation of effects of T and N type calcium channel blockers on the electroencephalogram recordings in Wistar Albino Glaxo/Rij rats, an absence epilepsy model
Durmus, Nedim; Gulturk, Sefa; Kaya, Tijen; Demir, Tuncer; Parlak, Mesut; Altun, Ahmet (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2015)Objectives: It is suggested that excessive calcium entry into neurons is the main triggering event in the initiation of epileptic discharges. We aimed to investigate the role of T and N type calcium channels in absence ... -
GÜNCEL PRATİK TIP EL KİTABI-2
Ataseven, Hilmi; Altun, Ahmet; Tıp Fakültesi (SİVAS CUMHURİYET ÜNİVERSİTESİ YAYINLARI, 2021)Kurumları değerli ve güçlü yapan en önemli faktörlerden birisi sürekliliktir. Bu sürekliliği sağlamanın en önemli yollarından bir tanesi ise geleneklerdir. Hele ki “Tıp” gibi eğitim nosyonunun özünü usta-çırak ilişkisinin ...