Browsing by Author "Ozdemir, Ercan"
Now showing items 21-27 of 27
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The nitric oxide-cGMP signaling pathway plays a significant role in tolerance to the analgesic effect of morphine
Ozdemir, Ercan; Bagcivan, Ihsan; Durmus, Nedim; Altun, Ahmet; Gursoy, Sinan (CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2011)Although the phenomenon of opioid tolerance has been widely investigated, neither opioid nor nonopioid mechanisms are completely understood. The aim of the present study was to investigate the role of the nitric oxide ... -
Physiological and Medical Responses to Anabolic-Androgenic Steroids: Review
Ozdemir, Ercan; Gulturk, Sefa (ORTADOGU AD PRES & PUBL CO, 2008)Anabolic-androgenic steroids (AAS) are synthetic derivatives of testosterone. Testosterone was isolated in the early 20th century. For the past 50 years anabolic steroids have been at the forefront of the controversy ... -
Rho-kinase inhibitors Y-27632 and fasudil prevent agonist-induced vasospasm in human radial artery
Disli, Olcay Murat; Ozdemir, Ercan; Berkan, Ocal; Bagcivan, Ihsan; Durmus, Nedim; Parlak, Ahmet (CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2009)Radial artery (RA) vasospasm remains a potential cause of early graft failure after coronary artery bypass graft surgery, despite pretreatment with alpha-adrenergic or calcium channel blockers. Our aim was to investigate ... -
Role of D-1/D-2 dopamin receptors antagonist perphenazine in morphine analgesia and tolerance in rats
Ozdemir, Ercan; Bagcivan, Ihsan; Gursoy, Sinan (ASSOC BASIC MEDICAL SCI FEDERATION BOSNIA & HERZEGOVINA SARAJEVO, 2013)While opioid receptors have been implicated in the development of tolerance, the subsequent mechanisms involved in these phenomena have not been completely understood. The purpose of this study was to investigate effects ... -
Serum selenium and plasma malondialdehyde levels and antioxidant enzyme activities in patients with obsessive-compulsive disorder
Ozdemir, Ercan; Cetinkaya, Sevil; Ersan, Serpil; Kucukosman, Seda; Ersan, E. Erdal (PERGAMON-ELSEVIER SCIENCE LTD, 2009)There is mounting evidence indicating that reactive free radical species are involved in initiation and development of many different forms of human pathologies including psychiatric disorders. In the present study, we ... -
Zimelidine attenuates the development of tolerance to morphine-induced antinociception
Ozdemir, Ercan; Gursoy, Sinan; Bagcivan, Ihsan; Durmus, Nedim; Altun, Ahmet (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2012)Objectives: The aim of this study was to investigate effect of zimelidine (a serotonin reuptake inhibitor) on morphine-induced tolerance in rats. Materials and Methods: Male Wistar albino rats weighing 160-180 g were used ...