dc.contributor.author | Kaygusuz, Kenan | |
dc.contributor.author | Gokce, Gokhan | |
dc.contributor.author | Gursoy, Sinan | |
dc.contributor.author | Ayan, Semih | |
dc.contributor.author | Mimaroglu, Caner | |
dc.contributor.author | Gultekin, Yener | |
dc.date.accessioned | 2019-07-27T12:10:23Z | |
dc.date.accessioned | 2019-07-28T10:15:39Z | |
dc.date.available | 2019-07-27T12:10:23Z | |
dc.date.available | 2019-07-28T10:15:39Z | |
dc.date.issued | 2008 | |
dc.identifier.issn | 0003-2999 | |
dc.identifier.uri | https://dx.doi.org/10.1213/01.ane.0000296453.75494.64 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/10446 | |
dc.description | WOS: 000251824300022 | en_US |
dc.description | PubMed ID: 18165564 | en_US |
dc.description.abstract | BACKGROUND: Dexmedetomidine, because it has both sedative and analgesic properties, may be suitable for conscious sedation during painful procedures. Extracor-Poreal shockwave lithotripsy (ESWL) is a minimal to mildly painful procedure that requires conscious sedation. We thus evaluated the utility of dexmedetomidine compared with propofol during an ESWL procedure. METHODS: Forty-six patients were randomly allocated into two groups to receive either dexmedetomidine or propofol for elective ESWL. Dexmedetomidine was infused at 6 mu g center dot kg(-1) center dot h(-1) for 10 min followed by an infusion rate of 0.2 mu g center dot kg(-1) center dot h(-1). Propofol was infused at 6 mg center dot kg(-1) center dot h(-1) for 10 min followed by an infusion of 2.4 mg center dot kg(-1) center dot h(-1). Fentanyl 1 mu g/kg IV was given to all patients 10 min before ESWL. Pain intensity was evaluated with a visual analog scale at 5-min intervals during ESWL (10-35 min). Sedation was determined using the Observer's Assessment of Alertness/Sedation. The Observer's Assessment of Alertness/ Sedation scores and hemodynamic and respiratory variables were recorded regularly during ESWL (35 min) and up to 85 min after. RESULTS: Forty patients were evaluated. Visual analog scale values with dexmedetomidine were significantly lower than those with propofol only at the 25-35 min assessments (P < 0.05). During sedation, the respiratory rate with dexmedetomidine was significantly slower but Spo(2) was significantly higher than with propofol (P < 0.05). Other clinical variables were similar (P > 0.05). CONCLUSION: A combination of dexmedetomidine with fentanyl can be used safely and effectively for sedation and analgesia during ESWL. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | en_US |
dc.relation.isversionof | 10.1213/01.ane.0000296453.75494.64 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.title | A comparison of sedation with dexmedetomidine or propofol during shockwave lithotripsy: A Randomized controlled trial | en_US |
dc.type | article | en_US |
dc.relation.journal | ANESTHESIA AND ANALGESIA | en_US |
dc.contributor.department | [Kaygusuz, Kenan -- Gursoy, Sinan -- Mimaroglu, Caner] Cumhuriyet Univ, Sch Med, Dept Anesthesiol, TR-58140 Sivas, Turkey -- [Gokce, Gokhan -- Ayan, Semih -- Gultekin, Yener] Cumhuriyet Univ, Sch Med, Dept Urol, TR-58140 Sivas, Turkey | en_US |
dc.identifier.volume | 106 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.endpage | 119 | en_US |
dc.identifier.startpage | 114 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |