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circRNAs in drug resistance of breast cancer
(2022)
Abstract: Breast cancer (BC) is the most common heterogeneous disease in women and one of the leading causes of cancer-related death. Surgery, chemotherapy, radiotherapy, hormone, and targeted therapy are the gold standards ...
Synthesis, Biological Evaluation and In Silico Studies of Some 2‐Substituted Benzoxazole Derivatives as Potential Anticancer Agents to Breast Cancer
(2022)
In an attempt to develop potent and selective anticancer agents, some 5- or 6- and N-substituted benzoxazol-2-carbox amide derivatives were designed, synthesized, and evaluated for their cyclooxygenase inhibitory, antioxidant, ...
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(HAZİRAN 20)
ABSTRACT: Mushrooms, which have been collected to meet the nutritional needs of the world for many years, have
gained medical importance thanks to the bioactive compounds they produce. Thanks to studies carried out to ...
Synthesis of Bis-Nicotinonitrile Derivatives and Investigations of Antimicrobial and Antibiofilm Activities
(Ekim 2023)
In this study aimed to the synthesis of novel bis-nicotinonitrile derivatives starting from 1,3-bis-chalcones and investigate their antimicrobial activity potentials. Bis-nicotinonitrile derivatives were synthesized from ...
Propolis nanoparticles synthesis and characterization with cytotoxic and apoptotic effects on breast cancer cells
(2023)
The aim of this work was to investigate the antiproliferative and pro-apoptotic effects of propolis
on human breast cancer cells using a simple and inexpensive nanoformulation. Various meth ods were used to characterize ...
Synthesis of Benzimidazole-1,2,4-triazole Derivatives as Potential Antifungal Agents Targeting 14α-Demethylase
(19.01.2023)
Invasive fungal infections (IFIs) are increasing as major infectious diseases
around the world, and the limited efficacy of existing medications has resulted in
substantial morbidity and death in patients due to the lack ...
New imidazole derivatives as aromatase inhibitor: Design, synthesis, biological activity, molecular docking, and computational ADME-Tox studies
(06.01.2023)
In this study, a series of imidazole derivatives was designed, synthesized, and evaluated for in vitro bi-
ological activity on the human breast cancer cell line MCF7 by MTT assay. To determine the selectivity
of the ...
Anti-adhesive effect of naturally obtained dicalcium phosphate dihydrate nanoparticles in the rat uterine wound model
(2023)
Objective: In this study, we aimed to compare the anti-adhesive effects of contractubex and dicalcium phosphate dihydrate
(DCPD) particles in rats treated with the uterine horn adhesion model. Materials and methods: Newly ...
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(Wiley-VCH GmbH, Weinheim, 2021/4)
A new class of cyanopyridine derivatives (10a–e and 11a–e) containing the
phenylurea unit was synthesized and tested against some metabolic enzymes
including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), ...
Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives
(19 Jan 202)
Pathological angiogenesis plays a critical role in tumorigenesis and tumor pro gression, and anti-angiogenesis therapies have evinced promising antitumor
effects in solid tumors. Chalcone skeleton has been regarded as a ...