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Synthesis, and docking studies of novel tetrazole-S-alkyl derivatives as antimicrobial agents
(07.01.2023)
A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their
antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC
22019) and ...
Nekroz
(31.12.2023)
Nekroz, hücrenin ani bir şok (radyasyon, ısı, kimyasallar, hipoksi, iskemi vb.),
mekanik stres gibi şiddetli çevresel bozulmalar ve donma-çözülme sonrası gibi
ciddi şekilde hasar gördüğü, enerjiden bağımsız bir hücre ...
Synthesis, biological evaluation and in silico studies of novel thiadiazole-hydrazone derivatives for carbonic anhydrase inhibitory and anticancer activities
(04.08.2023)
ABSTRACT
Thiadiazole and hydrazone derivatives (5a–5i) were synthesized
and their chemical structures were verified and described by
1
H NMR,
13
C NMR, and HRMS spectra. Three cancer cell lines
(MCF-7, MDA, and ...
Investigation of the Relationship between the Chemical Structures and the Cytotoxicity of Some Maleic Anhydride-Containing Copolymers as Polymeric Drug Carriers
(23.11.2023)
Polymer-based substances have been an important biomaterial in the advancement of drug
delivery systems as they enabled the controlled release of therapeutic agents in fixed doses with high
bioavailability, lower toxicity, ...
Antioksidan Miktarını Total Olarak Tayin Etme Yöntemleri
(31.12.2023)
Zararlı serbest radikallere karşı savaşan ve hücreleri koruyan moleküller olan
antioksidanlar tüm canlıların hayatta kalması için hayati önem taşır. Bu da bilim
insanlarını, gıdaların antioksidan özelliklerini ölçme ...
The Effect of Vitamins on Oxidation in Experimentally Diabetes Conditioned Rats
(27.07.2023)
Diabetes Mellitus (DM) is a metabolic disorder that is very
common in our society, is caused by a combination of hereditary
and environmental factors, and results in an increase in blood
glucose levels. Diabetes mellitus ...
INVESTIGATION OF SALVIA CADMICA’S ANTIOXIDANT PROPERTIES AND CYTOTOXIC PROPERTIES IN BREAST CANCER CELL LINE AND ITS APOPTOTIC INDUCTION
(30.05.2023)
Salvia cadmica is an endemic species known to have antioxidant, antimicrobial and aromatic
properties and the existence of Salvia species is known to date back to 753 BC. This species,
whose medicinal properties were ...
Use of newly synthetized magnetic Fe3O4 nanoparticles modified with hexadecyl trimethyl ammonium bromide for the sensitive analysis of antidepressant drugs, duloxetine and vilazodone in wastewater and urine samples
(2023)
A new enrichment and determination method involving HPLC-DAD analysis following magnetic solidphase
extraction (MSPE) was developed to detect trace amounts of two antidepressant drugs, namely,
duloxetine (DUL) and ...
Use of Fe3O4@MPTMS-Dithizone Magnetic Nanoparticles as Solid Phase Sorbent for Sensitive Analysis of Sibutramine Molecules in Herbal Slimming Products
(Bentham Science Publishers, June 07, 2)
Abstract: Background: A new enrichment and sensitive determination method, which includes HPLCDAD
analysis after Magnetic Solid Phase Extraction (MSPE), has been developed for trace analysis of
Sibutramine molecules in ...
Pharmaco-Metabolomics: Drug Effects on Metabolites
(Nova Science Publishers, 2023)
The development and advancements in technology, artificial intelligence,
and fields of bioinformatics, enabled the use of enormous data coming
from genes, transcripts, and proteins processed by the omics in medicine
as ...