Sivas Cumhuriyet Üniversitesi Eczacılık Fakültesi: Recent submissions
Now showing items 41-60 of 135
-
Azinphos-methyl and chlorfenvinphos pesticides determination using fabric phase sorptive extraction followed by high performance liquid chromatography-photodiode array detector
(Elsevier, 25 April 2)A reliable and efficient fabric phase sorptive extraction method was developed for the rapid analysis of azinphosmethyl and chlorfenvinphos pesticide residues in wastewater and fruit juice samples using high-performance liquid ... -
The Role of Nitric Oxide Pathway in the Anti-Epileptogenic Effect of Valproic Acid in the Pentylenetetrazole-Kindling Model in Rats
(02. 06. 20)Though valproic acid (VPA) is used to treat seizures, more investigations have been needed to understand the effect of VPA on the nitric oxide pathway in epilepsy. Our investigation aimed to study the effect of VPA on ... -
Investigation of the effect of sugammadex on glutamateinduced neurotoxicity in C6 cell line and the roles played by nitric oxide and oxidative stress pathways
(August 202)This experiment was intended to evaluate the effect of sugammadex on the cytotoxicity induced by glutamate, involving the nitric oxide and oxidative stress pathways. C6 glioma cells were used in the study. Glutamate ... -
Anticancer activity of lycopene in HT‑29 colon cancer cell line
(24. 03. 20)An inverse association between serum lycopene levels and the risk of cancers has been pointed out by many prospective and retrospective epidemiological studies which prompted more studies to be performed on animal models ... -
Mechanism of anticancer effect of gambogic acid on gastric signet ring cell carcinoma
(16. 08. 20)Gambogic acid has demonstrated inhibitory effects on the growth of various cancer cell types, such as breast cancer, pancreatic cancer, prostate cancer, lung cancer, and osteosarcoma. This study aims to investigate the ... -
Pharmaco-Metabolomics: Drug Effects on Metabolites
(Nova Science Publishers, 2023)The development and advancements in technology, artificial intelligence, and fields of bioinformatics, enabled the use of enormous data coming from genes, transcripts, and proteins processed by the omics in medicine as ... -
Phenolic content, antioxidant and antimicrobial activities evaluation and relationship of commercial spices in the lebanese market
(Kasım 2023)AbstractLebanese cuisine is renowned for its distinctive flavours and vibrant aromas. In Lebanese cuisine, spices are not just used for their flavour; they are also valued for their medicinal properties. This study consists ... -
Comparative analysis of pre-fermentation treatments on phenolic compounds and bioactivity in Vitis Vinifera var. Syrah and var. Cabernet Sauvignon grapes
(Mayıs 2023)This study investigated the effect of pre-fermentation treatments on the phenolic compounds and biological activities of red grapes of Vitis vinifera var. Syrah and var. Cabernet Sauvignon Syrah and Cabernet sauvignon musts ... -
Comparison of Chemical Profiles of Aronia melanocarpa Fruit Extracts
(Şubat 2023)The chokeberry plant, which is native to North America and the south of Canada, is a deciduous, shrub-shaped, berry-like plant belonging to the Rosaceae family, which survives for many years. It is seen as a plant that ... -
Novel ultra-stretchable and self-healing crosslinked poly (ethylene oxide)-cationic guar gum hydrogel
(Ekim 2023)AbstractHydrogels are three-dimensional structures with specific features that render them useful for biomedical applications, such as tissue engineering scaffolds, drug delivery systems, and wound dressings. In recent ... -
Cytotoxic, Antioxidant, Antibiofilm, and Antimicrobial Activities of Mushroom Species from Turkey
(HAZİRAN 20)ABSTRACT: Mushrooms, which have been collected to meet the nutritional needs of the world for many years, have gained medical importance thanks to the bioactive compounds they produce. Thanks to studies carried out to ... -
Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
(EYLÜL 2023)Abstract: Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene] silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1- methallyl-3-(3,4,5 ... -
Synthesis of Bis-Nicotinonitrile Derivatives and Investigations of Antimicrobial and Antibiofilm Activities
(Ekim 2023)In this study aimed to the synthesis of novel bis-nicotinonitrile derivatives starting from 1,3-bis-chalcones and investigate their antimicrobial activity potentials. Bis-nicotinonitrile derivatives were synthesized from ... -
Decoration, Characterization and Antimicrobial Activity Evaluation of Novel Nano-Based 1,2-Phenylenediamine Functionalized Maleic Anhydride-Allylphenyl Ether Conjugate
(Chemistry Europe, 02 October)1,2-Phenylenediamine (o-PDA) is a well-known fluorescent dye that enables the decoration of next generation chemotherapeutics. A novel o-PDA-functionalized maleic anhydride-allyl phenyl ether (poly(MA-alt-APE)/o-PDA ... -
BİYOLOJİK VERİTABANLARI KULLANILARAK BAKTERİYEL TOPOİZOMERAZ I HEDEFLİ TERAPÖTİK DNA APTAMERİ GELİŞTİRİLMESİ
(TÜSEB, 16.05.2023)DNA topoizomerazlar DNA topolojisini değiştirerek replikasyon ve transkripsiyon gibi canlılığı doğrudan ilgilendiren metabolik olaylarda görev alırlar. Bu nedenle kontrolsüz hücre bölünmesi/kanser ve patojenler ile savaşta ... -
Evaluation of the Anticancer and Biological Activities of Istaroxime via Ex Vivo Analyses, Molecular Docking and Conceptual Density Functional Theory Computations
(MDPI, 7 November)Cancer is a disease that occurs as a result of abnormal or uncontrolled growth of cells due to DNA damage, among many other causes. Certain cancer treatments aim to increase the excess of DNA breaks to such an extent that ... -
Poli[Maleik Anhidrit-Ko-Vinil Asetat] Kopolimerinin Doksorubisin/Doksorubisin Türevi Antikanser İlaçlarla Doğrusal Rasyonel Konjugatlarının Sentezi, Yapısal Karakterizasyonları Ve Çeşitli Kanser Hücreleri Üzerinde Sitotoksik/Antikanser Aktiviteleri
(20.01.2022)Nanotoksik özellikli poli[Maleik Anhidrit-Ko-Vinil Asetat] kopolimerinin sentezlenmesinden sonra ilaçlar tr için iyi bir taşıyıcı olduğu çeşitli deneysel veri ve analizlerle kanıtlanmıştır. Doksorubisin/Doksorubisin türevi ... -
Pyrazolyl‐Benzoxazinone Derivatives as Dual Hsp Inhibitors in Human Breast Cancer
(2022)Heat Shock Proteins (Hsps) play major role on the onset of several cancers. Metabolic rates of cancer cells are higher compared to that of untransformed cells. This accelerated rate force functional substrate proteins to ... -
Possible effects of clinoptilolite on small intestinal ischemia-reperfusion injury caused by experimental mesenteric artery occlusion
(2022)Objectives: Mesenteric ischemia is a surgical emergency caused by poor blood supply to the intestines. In ischemia,the decrease in blood flow to the tissue causes acidosis and cell death through anaerobic metabolism. ... -
The role of cytokeratin 19 levels in the determination of endometriosis stages
(2022)Objective/Aim: Endometrisosis, one of the most common gynecological disease, is characterized by the presence of endometriotic tissue outside of uterine cavity. The development and the validation of a simple blood ...