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INVESTIGATION OF THE ANTIMICROBIAL AGENT POTENTIAL OF 1,5-DIKETONE DERIVATIVES
(2021)
In this study, 1,5-diketones were synthesized by adding of cyclohexanone to five different chalcone derivatives (1a-e) via the 1,4-Michael addition reaction. Antimicrobial activities of synthesized compounds were investigated ...
Michael/Michael Addition Cascade of 2-Benzylidene-1- indanones with Chalcones: Synthesis and Biological Evaluations of Novel Polycyclic Compounds
(2021)
A series of novel racemic 2-aryloyl-1,3-diaryl-2,3,3a,8a-tetrahydrocyclopenta[a]inden-8(1H)-one derivatives were synthesized from KOtBu mediated Michael/Michael addition reaction of 2-benzylidene-1-indanones with chalcones ...
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(2021)
A new class of cyanopyridine derivatives (10a-e and 11a-e) containing the phenylurea unit was synthesized and tested against some metabolic enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and ...
Synthesis and Caracterizations of New Thiosemicarbazone and Thiazole Derivatives From Polycyclic Chiral 1,5- Diketones
(08.11.2023)
Thiosemicarbazone derivatives have a wide spectrum of biological
activity as well as various application areas such as
forming complexes with metals, using as intermediates in the
synthesis of heterocyclic bioactive ...
Synthesis of Bis-Nicotinonitrile Derivatives and Investigations of Antimicrobial and Antibiofilm Activities
(02.10.2023)
In this study aimed to the synthesis of novel bis-nicotinonitrile
derivatives starting from 1,3-bis-chalcones and investigate their
antimicrobial activity potentials. Bis-nicotinonitrile derivatives
were synthesized ...
Immobilization of pectinase on chitosan-alginate-clay composite beads: Experimental, DFT and molecular docking studies
(15.11.2023)
Pectinase was immobilized on chitosan-alginate-clay (CAC) beads using epichlorohydrin (ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by Fourier Transform Infrared Spectrophotometry (FTIR) ...