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Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)
Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ...
In vitro cytotoxic effects, in silico studies, some metabolic enzymes inhibition, and vibrational spectral analysis of novel β-amino alcohol compounds
(Elsevier, 05.02.2023)
In this study, an efficient single-step method for the preparation of β-amino alcohols ( 1 –3 ) in aqueous media was applied. The aim was to investigate the cytotoxic activity of Compounds 1, 2 and 3 in neu- roblastoma ...
Experimental and theoretical insights about the effect of some newly designed azomethine group-contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 05.09.2023)
We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ...
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 05.03.2023)
The main aims of anticancer drug development studies is to reduce the toxicity of the developed compound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ...
Determination of Nursing Students’ Resilience Levels, Care Behaviors, and Violence Management Competencies: A Descriptive, Cross-Sectional, and Relational Study
(WILEY, Hindawi, 2023)
Purpose. Violence is a factor that is frequently encountered in health systems and causes problems of various sizes. Nursing students who take an active role in health environments and are also inexperienced are also exposed ...
The effect of the Ebe Evimde application on the self-efficacy and anxiety levels of mothers: Randomized controlled trial
(DIGITAL HEALTH, April 25, )
Objective: Family health can be improved by making home visits with mobile applications. This study was carried out to
evaluate the effect of a mobile application and web-based software called Ebe Evimde (My Home Midwife), ...
The relationships between the COVID-19 fears of mothers and their mother-infant bonding and breastfeeding self-efficacy in the postpartum period
(Taylor&Francis Online, 2023)
ABSTRACT
Mothers who are in more sensitive and in a different state in the
postpartum period may think that the COVID-19 pandemic will affect
the health of their babies. This study was carried out to investigate ...
The investigation of host genetic variants of toll-like receptor 7 and 8 in COVID-19
(2023)
Toll-like receptors (TLRs) recognize infectious agents and play an important role in the innate immune system. Studies have suggested that TLR single nucleotide polymorphisms (SNPs) are associated with poor antiviral ...
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(MDPI, 01.12.2023)
Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body.
Objectives: In this study, we aimed to investigate the relationship between ...
Awareness, worry, and hope regarding climate change among nurses: A cross-sectional study
(2023)
ABSTRACT
Purpose: The aim of this study is to determine nurses’ awareness, worry and hope levels
about climate change.
Design and Methods: This cross-sectional study was conducted with 511 nurses. Data were
collected ...