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Now showing items 31-40 of 114
Determination of inhibitor activity of drugs against the COVID-19.
(2021)
Abstract: BACKGROUND: It is the SARS-CoV-2 virus, one of the most significant diseases of today’s world. Due to the high transmission of this disease, studies are ongoing to discover an inhibitor drug that can stop this ...
Are clarithromycin, azithromycin and their analogues effective in the treatment of COVID19?
(2021)
Abstract: BACKGROUND: SARS-CoV-2, which started in Wuhan and later affected the whole world, is the most important disease of the world today. Many ways to inhibit SARS-CoV-2 virus are sought to prevent the spread of this ...
Could boron compounds be effective against SARS-CoV-2?
(2021)
Abstract: BACKGROUND: Seven dioxaborole compounds are investigated in this study. Structural and spectral characterization is done at M062X/6-31+G(d,p) level in the water. Active sites of these compounds are determined ...
The use of laboratory parameters and computed tomography score to determine intensive care unit requirement in COVID-19
(2021)
Objectives
It is vital to determine the intensive care unit (ICU) requirement at an early stage to reduce the mortality rate in COVID-19 patients. The aim of the study was to find reliable predictive markers to determine ...
Mitochondrial Homeostasis and Mast Cells in Experimental Hepatic Ischemia-Reperfusion Injury of Rats.
(2022)
Background: Ischemia-reperfusion injury is a histopathological event and is an important cause of morbidity and mortality after hepatobiliary surgery. We aimed to investigate the protective effect of uridine on hepatic ...
Understanding the pathophysiological changes via untargeted metabolomics in COVID‐19 patients
(Wiley, 2021 Nisan)
Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease caused by a new strain of the coronavirus. There is limited data on the pathogenesis and the cellular responses of COVID-19. In this study, we aimed ...
A novel therapeutic approach to NASH: Both polyethylene glycol 3350 and lactulose reduce hepatic inflammation in C57BL/6J mice.
(2021)
Background. The gut-liver axis is one of the most emphasized topics in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Intestinal microbiota dysbiosis has been shown to be a predictor of disease severity and ...
Assessment of semaphorin 3A and semaphorin 7A levels in primary Sjogren's syndrome
(Springer, 2022/8/28)
Sjogren's syndrome (SS) is a chronic autoimmune connective tissue disease. Varying rates of system involvements may be seen in the course of the disease. Semaphorins has multifunctions in several physiological and pathological ...
Validation of Friedewald, Martin-Hopkins and Sampson low-density lipoprotein cholesterol equations
(2022/5/13)
Background: Low-density lipoprotein cholesterol (LDL-C) is an important biomarker for determining cardiovascular risk and regulating lipid lowering therapy. Therefore, the accurate estimation of LDL-C concentration is ...
Experimental, DFT and MD simulation studies of Mordant Black 11 dye adsorption onto polyaniline in aqueous solution
(Journal of Molecular Liquids, 2022)
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