Güncel Gönderiler: Sivas Cumhuriyet Üniversitesi Tıp Fakültesi
Toplam kayıt 224, listelenen: 21-40
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Effects of metformin and ganirelix on subcutaneous endometriosis in a mouse model of autophagy-related cell death/Otofaji ile iliskili hucrelerde subkutan endometriozis fare modelinde metformin ve genireliksin etkisi.
(Galenos Yayinevi Tic. Ltd., Eylül/2023)Objective This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. Materials and Methods Five groups were formed with eight ... -
Collaborative Clinical Research on Metabolomics
(23.10.2023)Metabolomikler nelerdir ve ilişkili klinik durumların güncel literatür eşliğinde araştırılması. Metabolomik analizlerin bu klinik durumlardaki hücresel yollakların araştırılması. -
Metabolomics in the Diagnosis of Pregnancy Complications
(2023/2)The pregnancy process is an intricate and unique period that requires control examinations to ensure the continuity of the well-being of the mother and the baby. The accompanying changes are also evident biologically, ... -
Dilay KARADEMİR, Mustafa KARADEMİR, İrem KÜÇÜKYILDIZ, Nazan YURTÇU, İlkin Seda CAN, Esra GÜLTÜRK
(2023/3/3)Abstract Amaç: Bu çalışmada amaç epilepsi tanısı almış ve antiepileptik ilaç kullanan gebelerde epilepsi hastalığının ve uygulanan antiepileptik tedavi protokolünün, anne, fetüs ve yenidoğan üzerine etkisinin değerlendi ... -
The Impact of Vitamin D and Acute Phase Proteins in the Diagnosis of Hyperemesis Gravidarum
(2023/9/30)ABSTRACT History Received: 11/04/2023 Accepted: 22/09/2023 Hyperemesis gravidarum (HG) has severe, dramatic consequences, and the cause of this severe disease has not yet been determined clearly. It is known that ... -
Effect of azomethine group containing compounds on gene profiles in Wnt and MAPK signal patterns in lung cancer cell line: In silico and in vitro analyses
(Elsevier, 2023/3/5)The main aims of anticancer drug development studies is to reduce the toxicity of the developed com pound and maximize the effectiveness, as well as the discovery of artificial and natural compounds. In recent years, ... -
Biological evaluation and in silico molecular docking studies of Abies cilicica (Antoine & Kotschy) Carrière) resin
(Elsevier, 2023/9/15)Abies cilicica (Antoine & Kotschy) Carri`ere) is an endemic species of industrial and medicinal importance. The resin obtained from this plant is effective for different diseases. The chemical content of the ethanol ... -
Experimental and theoretical insights about the effect of some newly designed azomethine group‐contained macroheterocycles on oxidative stress and DNA repair gene profiles in neuroblastoma cell lines
(Elsevier, 2023/8/5)We report herein the synthesis of new azomethine group containing forty-, sixty-eight- and seventy- two-membered macroheterocyclic compounds and the investigation of their activity against the neurob- lastoma cell line. ... -
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(Bentham Science Publishers, 01.12.2023)Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body. Objectives: In this study, we aimed to investigate the relationship ... -
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 28.09.2023)We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were ... -
Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ... -
The effect of platelet-rich plasma on intra-abdominal adhesions in rabbit uterine horn model
(2023)Objective: This study was carried out to investigate the effect of autologous platelet-rich plasma (PRP) on intra-abdominal adhesion at the cesarean section incision line in the uterus. Material and methods: As ... -
Effects of polyamine synthesis enzymes on angiogenesis and apoptosis during endometriosis
(2023)Objectives: Since we assumed that endometriosis is a benign cell division disorder, our study was conducted to investigate the effects of the relationships between polyamine synthesis and angiogenesis in the formation of ... -
Novel Bioactive Glass/Graphene Oxide-Coated Surgical Sutures for Soft Tissue Regeneration
(2023)The combination of a commercially available PGLA (poly[glycolide-co-l-lactide]), 90:10% suture material with bioactive bioglass nanopowders (BGNs) and graphene oxide (GO)-doped BGNs offers new opportunities for the clinical ... -
Histopathological Evaluation of Endometrial Biopsies in Different Age Groups: A Tertiary Care Experience in Turkey
(2023)Background: An endometrial biopsy primarily aims to determine endometrial cancer and hyperplasia with atypia at an early stage. Objectives: This study aims to evaluate the indications, histopathological diagnoses, and the ... -
Anti-adhesive effect of naturally obtained dicalcium phosphate dihydrate nanoparticles in the rat uterine wound model
(2023)Objective: In this study, we aimed to compare the anti-adhesive effects of contractubex and dicalcium phosphate dihydrate (DCPD) particles in rats treated with the uterine horn adhesion model. Materials and methods: Newly ... -
The Effect on the Birth Process of Endogenous Oxytocin Release Via Coitus at Home in Pregnant Women in the Latent Phase
(Georg Thieme Verlag KG, 2023)Objectives This study was conducted to determine the effect of endogenous oxytocin release via coitus at home on the delivery process in pregnant women who were not hospitalized in the latent phase. Background For healthy ... -
The Turkish version of the problem areas in diabetes-parents of teens (P-PAID-T): Cross-cultural adaptation, reliability, and validity
(2023)Objective: To examine the Turkish validity and reliability of the Problem Areas in Diabetes- Parents of Teens (P PAID-T) scale and its psychometric properties for determining the parents’ diabetes-related distress. Methods: ... -
Psychometric Properties of the Turkish Validity and Reliability of the Parent Diabetes Distress Scale
(2023)Abstract Objective: The aim of this study was to evaluate the validity and reliability of the Turkish translation of the Parent Diabetes Distress Scale (PDDS). Methods: The PDDS is a 5-point Likert-type scale with 20 ... -
Sleep quality and glycemic control in children and adolescents with type 1 diabetes mellitus
(2023)Abstract. – OBJECTIVE: This study aimed to investigate the frequency of sleep disorders, and the relationship between glycemic control and sleep characteristics in diabetic children and adolescents. PATIENTS AND ...