| dc.description.abstract | In the study, a fast and green natural deep eutectic solvent based ultrasound-assisted liquid liquid
microextraction (NDES-UALLME) were proposed for the determination and extraction of
deltamethrin in food samples using UV/Vis spectrophotometry. The extraction step was based on
ion-pair formation between deltamethrin and levulinic acid-tetraethylammonium bromide (as
extraction solvent) at pH 5.5, and then extraction of deltamethrin into micro-drops of extraction
solvent by using tetrahydrofuran. Levulinic acid-based natural deep eutectic solvents composed
of natural, green compounds, i.e., choline acetyl chloride, tetrabutylammonium bromide,
tetraethylammonium chloride and tetraethylammonium bromide were used for the first time as
extraction solvents for extraction of deltamethrin. The NDES-UALLME procedure allowed to exclude
matrixes effects and increase enrichment factor (283) of deltamethrin. Several key factors,
including the type and the volume of extraction solvent, the pH of sample solution, ultrasound
time, extraction temperature, ionic strength and sample volume were optimized in detail. At optimized
conditions, the NDES-UALLME procedure was characterized by low limit of detection
(2.4 ng mL−1), a wide linear dynamic range (8–950 ng mL−1), quantitative recoveries (93 ± 4%-
103 ± 2%) and acceptable relative standard deviations (2.9%≤). The validation of NDESUALLME
procedure was carried out using recovery tests, intraday and intraday studies. The applicability
of NDES-UALLME procedure was confirmed by the assay of deltamethrin in real food
samples. | tr |
