dc.contributor.author | Gökçe, Göksel; Karavana, Sinem Yaprak; Bağrıyanık, Hüsnü Alper; Pekçetin, Çetin; Alğın Yapar, Evren; Aybar Tural, Gülşen; Gökçe, Evren Homan. | |
dc.date.accessioned | 2023-06-21T08:45:34Z | |
dc.date.available | 2023-06-21T08:45:34Z | |
dc.date.issued | 2022 | tr |
dc.identifier.citation | GÖKÇE, GÖKSEL; KARAVANA, SİNEM YAPRAK; BAĞRIYANIK, HÜSNÜ ALPER; PEKÇETİN, ÇETİN; YAPAR, EVREN ALĞIN; TURAL, GÜLŞEN AYBAR; and GÖKÇE, EVREN HOMAN (2022) "Design and in vitro, in vivo evaluation of antioxidant bioadhesive gelsfor burn treatment," Turkish Journal of Biology: Vol. 46: No. 3, Article 6. https://doi.org/10.55730/1300-0152.2613 | tr |
dc.identifier.uri | https://doi.org/10.55730/1300-0152.2613 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/13822 | |
dc.description.abstract | Abstract
Burn wounds are frequently encountered health problems, which need a new treatment approach especially in terms of good patient compliance. Availability of use of antioxidant agents and bio-adhesive gels in tissue healing can be an alternative as a new approach for wound healing. Antioxidant taurine containing bio-adhesive gels were prepared by using carbopol (CP) 940 and 934. Rheological and texture analyses were carried out on bio-adhesive gels for in vitro characterization. Wound model on Wistar rats was used to evaluate the in vivo evaluation of gels. Rheological and texture analyses showed that a carbopol bioadhesive gel has acceptable topically use dosage characteristics and in combination with Taurine it presented a successful wound healing effect via antioxidant parameters. In conclusion, bio-adhesive CP 940 (2%) gel containing 50 mM taurine could be promising in the treatment of burns by balancing oxidative stress. | tr |
dc.language.iso | eng | tr |
dc.publisher | TUBİTAK | tr |
dc.relation.isversionof | 10.55730 | tr |
dc.rights | info:eu-repo/semantics/openAccess | tr |
dc.subject | Taurine, antioxidant, bio-adhesive gel, burn wound model | tr |
dc.title | Design and in vitro in vivo evaluation of antioxidant bioadhesive gels for burn treatment | tr |
dc.type | article | tr |
dc.contributor.department | Eczacılık Fakültesi | tr |
dc.contributor.authorID | 0000-0002-6504-4608 | tr |
dc.identifier.volume | 46 | tr |
dc.identifier.issue | 3 | tr |
dc.identifier.endpage | 262 | tr |
dc.identifier.startpage | 251 | tr |
dc.relation.publicationcategory | Uluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanı | tr |