Preparation and evaluation of a propolis ointment for skin nourishing and healing.
Citation
Gurer, Eda Sonmez; Seker, Ibrahim Tugkan; Guzel, Imren Esenturk; Yapar, Evren Algın; Dosler, Sibel. Pakistan Journal of Pharmaceutical Sciences. Nov2022, Vol. 35 Issue 6, p1565-1571. 7p. DOI: 10.36721/PJPS.2022.35.6.REG.1565-1571.1. , Veritabanı: The Belt and Road Initiative Reference SourceAbstract
Propolis is a resinous substance containing aromatic acids, esters, volatile compounds, hydrocarbons, steroids,
enzymes, flavonoids, vitamins and minerals. In this direction it has nutrient, antibacterial and antioxidant properties due
to its complex structure and content. In this study it was aimed to prepare a propolis ointment with a base of occlusive
and emollient properties for nourishing and healing of skin damaged by environmental effects. Six formulations were
prepared by using vaseline, lanolin, glycerine and different types of crude propolis. According to physical examinations
only the ointment formulations prepared with ethanolic propolis extracts at two different concentrations were found as
successful. Successful formulation including 1:5 propolis: Ethanol extract was evaluated by physical controls, mechanic
tests, antimicrobial tests and stability evaluation. Results showed that prepared propolis ointment has a creamy yellow
colour with an acceptable odour, homogeny and a good spreadability texture and has a good stability at 40oC and 25oC
and for 2 and 3 months respectively. And it presented mild antibacterial effects on E. coli and S. aureus strains, which
was acceptable for a frequent use for cosmetic purposes. As a conclusion prepared propolis ointment can be a good
candidate for a cosmetic ointment for skin nutrition and healing purposes.
Source
Pakistan Journal of Pharmaceutical SciencesVolume
35Issue
6URI
https://eds.p.ebscohost.com/eds/pdfviewer/pdfviewer?vid=0&sid=bfeed657-0dc5-45fa-8b2a-cc5478500953%40redishttps://hdl.handle.net/20.500.12418/13837