dc.contributor.author | Güzel,Emre | |
dc.contributor.author | Koçyiğit,Ümit M. | |
dc.contributor.author | Taslimi, Parham | |
dc.contributor.author | Gülçin,İlhami | |
dc.contributor.author | Erkan Sultan | |
dc.contributor.author | Nebioğlu, Mehmet | |
dc.contributor.author | Arslan,Barış S | |
dc.contributor.author | Şişman,İlkay | |
dc.date.accessioned | 2023-06-21T13:20:49Z | |
dc.date.available | 2023-06-21T13:20:49Z | |
dc.date.issued | 2022/01/26 | tr |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/13858 | |
dc.description.abstract | n this study, the preparation, aggregation behavior and investigation of carbonic anhydrase and cholinesterase enzyme inhibition features of non-peripherally (4-isopropylbenzyl)oxy-substituted phthalocyanines (4–6) are reported for the first time. The chemical structures of these new phthalocyanines were elucidated by UV-Vis (ultraviolet-visible), FT-IR (Fourier transform infrared spectrometry), NMR (nuclear magnetic resonance) and MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight) mass spectrometry. The substitution of 4-isopropylbenzyl)oxy groups benefits a remarkable solubility and redshift of the phthalocyanines Q-band. Also, these complexes were tested against some enzymes such as butyrylcholinesterase enzyme, human carbonic anhydrase I and II isoforms and acetylcholinesterase enzyme. The phthalocyanine complexes showed Ki values of in the range of 478.13 ± 57.25–887 | tr |
dc.publisher | Taylor & Francis | tr |
dc.rights | info:eu-repo/semantics/openAccess | tr |
dc.title | Phthalocyanine complexes with (4-isopropylbenzyl) oxy substituents: preparation and evaluation of anti-carbonic anhydrase, anticholinesterase enzymes and molecular docking studies | tr |
dc.type | animation | tr |
dc.relation.journal | Journal of Biomolecular Structure and Dynamics | tr |
dc.contributor.department | Eczacılık Fakültesi | tr |
dc.contributor.authorID | 0000-0001-8710-2912 | tr |
dc.identifier.volume | 40 | tr |
dc.identifier.issue | 2 | tr |
dc.identifier.endpage | 741 | tr |
dc.identifier.startpage | 733 | tr |
dc.relation.publicationcategory | Ulusal Hakemli Dergide Makale - Kurum Öğretim Elemanı | tr |