Investigation of changes in serum thiols and neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume/platelet count ratio indices in cats undergoing ovariohysterectomy
Abstract
The aim of this study was to investigate complete blood indices
[neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte
ratio (MLR), platelet-to-lymphocyte ratio (PLR) and mean platelet
volume/platelet count ratio (MPV/PLT)] and thiols (native and
thiol) in cats undergoing ovariohysterectomy (OHE). The study
sample comprised a total of 10 female cats of mixed breeds.
Ovariohysterectomy operation was performed under Ketamine/
Xylazine anesthesia with the appropriate technique. Blood samples
were collected from the cephalic vein pre-OHE and post-OHE at
2 h, 24 h, and 7 d. Total and native thiol levels in the serum were
analyzed using a colorimetric technique, and whole blood analysis
was carried out using anticoagulant tubes. White Blood Cell (WBC)
and neutrophil increased significantly at 2 h post-OHE, peaked at
24 h post-OHE, then returned to baseline levels by 7 d (P<0.001). The
lymphocyte and thiols decreased at 2 h, 24 h, and 7 d post-OHE, and
the lowest lymphocyte count was observed at 24 h (P<0.001). The
lowest monocyte count was observed on d 7 post-OHE (P<0.001). NLR
increased significantly 2 h after OHE, peaked at 24 h after OHE, and
remained high on d 7 (P<0.001). MLR increased at 2 h, peaked at 24
h, then returned to baseline levels on d 7 (P<0.001). PLR increased
gradually and peaked at 24 h and on d 7 (P<0.001). MPV/PLT after
OHE was statistically lowest on d 7 (P<0.05). A negative correlation
was determined between NLR, MLR, PLR, and thiols (P<0.001). In
conclusion, thiols and complete blood indices (NLR, MLR, and PLR)
may be important in the assessment of inflammation and stress
responses after OHE in cats.
Source
REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIASVolume
xxxıııIssue
rcfcv-e33260URI
https://produccioncientificaluz.org/index.php/cientifica/article/view/40141https://hdl.handle.net/20.500.12418/14295
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