dc.contributor.author | Kurt, Begüm | |
dc.contributor.author | Yıldız, Çağlar | |
dc.contributor.author | Koç, Tülay | |
dc.contributor.author | Özkaya, Kurt, Neşe | |
dc.contributor.author | Çelikgün, Serkan | |
dc.date.accessioned | 2024-03-06T09:12:30Z | |
dc.date.available | 2024-03-06T09:12:30Z | |
dc.date.issued | 2023 | tr |
dc.identifier.issn | 0009-7411 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12418/14734 | |
dc.description.abstract | Objective:
This study was carried out to investigate the effect of autologous platelet-rich plasma (PRP) on intra-abdominal adhesion at the cesarean section incision line in the uterus.
Material and methods:
As experimental animals 16 white New Zealand rabbits, 5-months-old, unmated, were used. Animals were divided into two groups the control group and PRP application group. In each group, a transverse incision was made to the uterus to mimic the cesarean section and sutured. Relaparotomy was performed 21 days after the first operation.
Results:
When the groups were evaluated in terms of inflammation, there was a significant difference between the two groups. When the groups were evaluated in terms of Mason’s Trichrome staining and fibrosis, There was a significant difference between groups. When the groups were evaluated in terms of vascular endothelial growth factor-1, there was also a significant difference between the groups. In an experimental rabbit uterine horn adhesion model, PRP is effective in preventing post-operative adhesion formation.
Conclusions:
This result may guide clinical studies using autologous PRP to prevent post-operative adhesion formation after gynecological operations. | tr |
dc.description.sponsorship | CUBAP with project number T-2022-942 | tr |
dc.language.iso | eng | tr |
dc.relation.isversionof | 10.24875/ciru.23000070 | tr |
dc.rights | info:eu-repo/semantics/openAccess | tr |
dc.title | The effect of platelet-rich plasma on intra-abdominal adhesions in rabbit uterine horn model | tr |
dc.type | article | tr |
dc.relation.journal | Cirugía y cirujanos | tr |
dc.contributor.department | Tıp Fakültesi | tr |
dc.contributor.authorID | 0000-0002-7166-3130 | tr |
dc.identifier.volume | 91 | tr |
dc.identifier.issue | 6 | tr |
dc.relation.publicationcategory | Rapor | tr |