Metabolomics in the Diagnosis of Pregnancy Complications
Date
2023/2Metadata
Show full item recordAbstract
The pregnancy process is an intricate and unique period that requires
control examinations to ensure the continuity of the well-being of the
mother and the baby. The accompanying changes are also evident
biologically, physiologically, psychologically, and socially. Several
factors must be considered to determine when a woman's pregnancy is at
risk and when unfavorable pregnancy outcomes will occur. Biomedical
indicators are critical in medicine. Studies show that the variables in these
indicators are vital in determining the risk status. Once the metabolic
pathways are understood clearly in healthy and diseased conditions, we
can gain more applicable information on disease mechanisms and precise
treatment approaches. The prenatal medicine practices require the
development of novel non-invasive approaches that cover diverse
categories of diseases with lower rates of false-positives. Metabolomics
for this purpose has the potential of great advantage. Metabolomic
studies measure and analyze the biochemistry products of cells. As a
biomarker, metabolomics may uncover new diagnostic and therapeutic
approaches. This chapter reviews the idea and utilization of
metabolomics for maternal health and perinatal medicine, emphasizing
the latest developments in metabolomics studies and the research agenda.
In addition, the existence of studies that will increase our knowledge about the etiopathogenesis of maternal complications is exciting and
promising.