Browsing Temel Tıp Bilimleri Bölümü by Title
Now showing items 36-55 of 86
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Galium aparine L. protects against acetaminophen-induced hepatotoxicity in rats
(Elsevier, 2022)The toxicity of acetaminophen (N-acetyl-para-aminophenol (APAP)) is the most frequent cause of drug-induced liver damage. Galium aparine L. (GA) is traditionally used to treat jaundice. We aimed to investigate the ... -
Hypothalamo-pituitary insufficiency associated with ectrodactyly-ectodermal dysplasia-clefting syndrome
(2009)Ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome is characterized by ectodermal dysplasia, ectrodactyly and facial clefting with multiple congenital anomalies such as urinary tract anomaly, lacrimal duct obstruction, ... -
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 28.09.2023)We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were ... -
Increased endoplasmic reticulum stress might be related to brain damage in hepatic ischemia-reperfusion injury
(2023)Objectives: Our study aimed to investigate the role of endoplasmic reticulum stress (ER) in brain damage following hepatic ischemia-reperfusion (HIR) injury. Specifically, we characterized the expression of markers of ... -
Investigating the Healing Effect of Hyperici Oleum and Triticum vulgare on Septal Perforation in Rats: A Preliminary Study
(2023)Objective: The aim of this study was to investigate histopathologically the possible beneficial effects of hyperici oleum and Triticum vulgare, having anti-inflammatory, antioxidant, and antiproliferative properties, on ... -
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study
(Bentham Science Publishers, 01.12.2023)Background: Fibromyalgia is a soft tissue rheumatism characterized by chronic and widespread musculoskeletal pain at specific points in the body. Objectives: In this study, we aimed to investigate the relationship ... -
Investigation of the mechanisms involved in anticancer effect of glucosamine sulfate on SH-SY5Y cell line
(Bratislavske lekarske listy, 2022)Aim: Glucosamine derivatives have been found to have anticancer effects in many cancer cell lines in previous investigations. The effect of glucosamine sulfate on neuroblastoma, however, is uncertain. The potential cytotoxic ... -
ISI ŞOK PROTEİN 70 (HSP70) VE KANSER
(Efe Akademik Yayıncılık, 2022)Kardiyovasküler hastalıklardan sonra ikinci sıradaki ölüm nedeni olarak gösterilen kanserin, insidansı ve ölüm oranı tüm dünyada hızla artmaktadır. Amerikan Kanser Derneği'nin yakın tarihli bir raporuna göre, 2020'de ... -
Joint Research on Perinatology
(12.07.2023)Medical and surgical care have made considerable progress in the last two decades in the care of the mother, fetus, and neonate. Most of the improvement in outcomes has been related to advances in diagnostic and therapeutic ... -
Leukotriene metabolism and proiflammatory cytokines in Crimean Congo hemorrhagic fever
(01.01.2023)Crimean–Congo hemorrhagic fever (CCHF) is an emerging acute viral infection disease, yet its pathophysiology remains largely uncharacterized. Lipid mediators are molecules that play numerous roles in the physiologic and ... -
Long noncoding RNA expression analysis in Crimean Congo hemorrhagic fever patients
(Wiley, 2022)Crimean Congo hemorrhagic fever (CCHF) is an acute viral infection that can cause death. The detection of host transcriptome is important for understanding differences in the pathogenesis of the disease. Long noncoding ... -
Manyetik Alanın Kanser Hücreleri Üzerine Etkisini Biyokimyasal ve Biyofiziksel Açıdan İnceleme
(İksad Yayınevi, 2022)jhj -
Medical Students' Views and Attitudes toward Vaccine Refusal during the COVID-19 Pandemic: A Multicenter Study
(20.04.2024)Background: The rapid development and production of COVID-19 vaccines have raised concerns about their safety and efficacy, which have contributed to vaccine hesitancy among some people. Objectives: This study aimed to ... -
Melatonin levels and microRNA (miRNA) relative expression profile in the follicular ambient microenvironment in patients undergoing in vitro fertilization process
(2021)Abstract Purpose Intrafollicular fluid (IFF) melatonin plays a decisive role in maintaining granulosa cells’ DNA integrity and protects them against apoptosis. It reduces oxidative stress and improves the oocyte quality ... -
Metabolomics in the Diagnosis of Pregnancy Complications
(2023/2)The pregnancy process is an intricate and unique period that requires control examinations to ensure the continuity of the well-being of the mother and the baby. The accompanying changes are also evident biologically, ... -
Mide Kanser ve Omik Tabanlı Analizler
(2022)Çoğu normal doku hücresiyle karşılaştırıldığında kanser hücrelerinde belirgin olarak farklı metabolik yolaklarda değişiklikler görülür. Omik tabanlı veri entegrasyonu, mide kanseri araştırmalarında kapsamlı bir şekilde ... -
Mitochondrial Homeostasis and Mast Cells in Experimental Hepatic Ischemia-Reperfusion Injury of Rats.
(2022)Background: Ischemia-reperfusion injury is a histopathological event and is an important cause of morbidity and mortality after hepatobiliary surgery. We aimed to investigate the protective effect of uridine on hepatic ... -
MİDE KANSERİ VE DENEY HAYVANLARI MODELLEMELERİ
(2022)Mide karsinogeneziyle ilgili çalışmalar için çeşitli mide fenotiplerine sahip çok sayıda hayvan modeli mevcuttur. Mide kanseriyle ilgili mekanizmaları anlamak, önleyici ve terapötik müdahaleler tasarlamak için hayvan ... -
MİDE KANSERİ VE HÜCRE KÜLTÜRÜ
(Efe Akademik Yayıncılık, 2022)Mide kanseri, gastrointestinal tümörlere neden olan, insan hayatı ve sağlığı için ciddi bir tehdit oluşturan yaygın bir hastalıktır. Hücre kültürü tekniği, diğer birçok kanser türünde olduğu gibi, mide kanseri ... -
Nanoparticles with PDT and PTT synergistic properties working with dual NIR-light source simultaneously
(2021)A non-toxic nano system using a cleverly designed dual light can be an important treatment strategy in cancer therapy. Here, we propose a unique concept of synergistic non-toxic nanoplatform, which operates with dual ...