Browsing Temel Tıp Bilimleri Bölümü by Title
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A novel therapeutic approach to NASH: Both polyethylene glycol 3350 and lactulose reduce hepatic inflammation in C57BL/6J mice.
(2021)Background. The gut-liver axis is one of the most emphasized topics in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Intestinal microbiota dysbiosis has been shown to be a predictor of disease severity and ... -
A significant association between rs2295190 polymorphism of the ESR1 gene and fibromyalgia syndrome
(CMB Association Publiher, 2022)Fibromyalgia syndrome (FMS) is a multifactorial disease characterized by chronic diffuse pain. Genetic factors are also involved in the etiology. However, there is not enough information on the genetic factors that ... -
Adaptation of the evidence-based practices attitude scale-15 in Turkish family medicine residents
(Wiley, 08.2021)Aims: Aim of this study is to translate and apply a cross-cultural adaptation of the Evidence-Based Practice Attitude Scale (EBPAS) in Turkish and investigate its validity and reliability. Methods: The original EBPAS-15 ... -
AKILCI LABORATUVAR İSTEMİ YAPABİLME
(2022)Clinicians in healthcare institutions often use laboratory data when making decisions about patients.When laboratory requests are made correctly, it contributes significantly to the diagnosis and treatment of the patient, ... -
ALLYL FUNCTIONALIZED BENZIMIDAZOLIUM-DERIVED AG(I)-N-HETEROCYCLIC CARBENE COMPLEXES: ANTI-BIOFILM AND ANTIMICROBIAL PROPERTIES
(April 2022)Microorganisms in the biofilm structure cause severe health problems and economic losses. Therefore, it is very important to design and screen anti-biofilm molecules that can solve the related problems. This paper is aimed ... -
Anti-adhesive effect of naturally obtained dicalcium phosphate dihydrate nanoparticles in the rat uterine wound model
(2023)Objective: In this study, we aimed to compare the anti-adhesive effects of contractubex and dicalcium phosphate dihydrate (DCPD) particles in rats treated with the uterine horn adhesion model. Materials and methods: Newly ... -
Anticancer activity, hTERT expression and telomere length analysis in SH-SY5Y neuroblastoma cell lines applied to docetaxel
(Elsevier, 05.02.2023)Neuroblastoma is the most common extracranial solid tumor of infancy in a broad range of clinical courses, ranging from spontaneous regression to fatal progression. Telomere maintenance plays an impor- tant role in genome ... -
Antimicrobial activity, inhibition of biofilm formation, and molecular docking study of novel Ag-NHC complexes
(Elsevier, 15/09/2021)In this study, we reported the synthesis of a new series of Silver(I)-N-heterocyclic carbene complexes which were obtained from the corresponding new N-heterocyclic carbene (NHC) precursors. All new compounds were characterized ... -
Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag(I)-NHC complexes
(John Wiley & Sons Ltd, December 2)Benzimidazole type N-heterocyclic carbene molecules and their metal complexes have well-known biological activity. Elemental silver and silver complexes also have antibacterial and antifungal activity. In this study, ... -
Antimicrobial synergism and antibiofilm activities of Pelargonium graveolens, Rosemary officinalis, and Mentha piperita essential oils against extreme drug-resistant Acinetobacter baumannii clinical isolates
(28 Mart 20)Rosemary officinalis L., Pelargonium graveolens L., and Mentha piperita L., essential oils are used by complementary medicine specialists simultaneously with traditional antibiotics for treatment purposes. The chemical ... -
Antimicrobial synergism and antibiofilm activities of Pelargonium graveolens, Rosemary officinalis, and Mentha piperita essential oils against extreme drug-resistant Acinetobacter baumannii clinical isolates
(De Gruyter, March 2022)Abstract: Rosemary officinalis L., Pelargonium graveolens L., and Mentha piperita L., essential oils are used by complementary medicine specialists simultaneously with traditional antibiotics for treatment purposes. The ... -
Antimicrobial, anti-biofilm and cytotoxic properties of methallyl functionalized benzimidazolium-derived Ag(I)-Nheterocyclic carbene complexes
(April 2022)Purpose: To investigate the antimicrobial, antibiofilm, and cytotoxicity properties of methallyl substituted benzimidazolium-based, silver-bound N-heterocyclic carbene (Ag(I)-NHC) complexes, with respect to their potential ... -
Antimicrobially effective protein-loaded metal chelated chitosan composite
(1 Ağustos )The immobilization of lysozyme onto a novel synthetic metal chelator composite based on chitosan/ PAA-PMA (chitosan/acrylamide-maleic acid) and its effect on antimicrobial activity were the aim of the current study. ... -
Aspirin attenuates morphine antinociceptive tolerance in rats with diabetic neuropathy by inhibiting apoptosis in the dorsal root ganglia
(2023)Morphine is a drug used in chronic pain such as diabetic neuropathy, but the development of tolerance to its antinoci ceptive efect is an important clinical problem. Aspirin is an analgesic and antiapoptotic drug used in ... -
Assessment of semaphorin 3A and semaphorin 7A levels in primary Sjogren's syndrome
(Springer, 2022/8/28)Sjogren's syndrome (SS) is a chronic autoimmune connective tissue disease. Varying rates of system involvements may be seen in the course of the disease. Semaphorins has multifunctions in several physiological and pathological ... -
Ateroskleroz Hastalarında Koroner Arter Plaklarının Yeniden Modellenmesinde Etkili Epigenetik Mekanizmaların Araştırılması
(2022)Kardiyovasküler hastalıklar, WHO verilerine göre tüm dünyada ölümlerin önde gelen sebebidir. Kardiyovasküler hastalık portföyünün tipik temsilcisi niteliğindeki koroner arter hastalığı, olguların çoğunda, damar intima-medya ... -
Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
(27 Septemb)Abstract Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene] silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1-methallyl-3-(3,4,5-tr ... -
Best Practices of Feature Selection in Multi-Omics Data
(IGI Global, 2023)Today, there is an increase in data in many areas. With this increase, the number and variety of the variables to be evaluated also increases. The increase in data and variables became a situation that needed to be solved ... -
Biological evaluation and in silico molecular docking studies of Abies cilicica (Antoine & Kotschy) Carrière) resin
(Elsevier, 2023/9/15)Abies cilicica (Antoine & Kotschy) Carri`ere) is an endemic species of industrial and medicinal importance. The resin obtained from this plant is effective for different diseases. The chemical content of the ethanol ... -
Breastfeeding frequency of primary healthcare professionals and effective factors
(Wiley, 10.2021)Background: To determine the frequency of breastfeeding of mothers working in primary care, the differences between different employment groups, and the effective factors. Methods: This descriptive research study was ...