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RNA N6-Methyladenosine Pathway Writer Genes Expression Levels and Clinical Severity of Infection in Covid-19 Patients
(2023)
Abstract—Epigenetic modifications are known to be effective in the severity and mortality rate of SARS CoV-2 infection. N6-methyladenosin (m6A) is a posttranscriptional modification that is carried out by m6A
methyltransferases ...
Increased endoplasmic reticulum stress might be related to brain damage in hepatic ischemia-reperfusion injury
(2023)
Objectives: Our study aimed to investigate the role of
endoplasmic reticulum stress (ER) in brain damage following
hepatic ischemia-reperfusion (HIR) injury. Specifically, we
characterized the expression of markers of ...
The mechanism of anticancer effects of some pyrrolopyrimidine derivatives on HT-29 human colon cancer cells
(2023)
In the present work, the mechanism of anticancer activity of some pyrrolopyrimidine derivatives was evaluated.
Compounds 5 and 8 exhibiting significant antiproliferative activity against HT-29 cells with IC50 values of ...
Novel Bioactive Glass/Graphene Oxide-Coated Surgical Sutures for Soft Tissue Regeneration
(2023)
The combination of a commercially available PGLA
(poly[glycolide-co-L-lactide]), 90:10% suture material with bio active bioglass nanopowders (BGNs) and graphene oxide (GO)-
doped BGNs offers new opportunities for the ...
Anti-adhesive effect of naturally obtained dicalcium phosphate dihydrate nanoparticles in the rat uterine wound model
(2023)
Objective: In this study, we aimed to compare the anti-adhesive effects of contractubex and dicalcium phosphate dihydrate
(DCPD) particles in rats treated with the uterine horn adhesion model. Materials and methods: Newly ...
Investigating the Healing Effect of Hyperici Oleum and Triticum vulgare on Septal Perforation in Rats: A Preliminary Study
(2023)
Objective: The aim of this study was to investigate histopathologically the possible beneficial effects of hyperici oleum and Triticum vulgare,
having anti-inflammatory, antioxidant, and antiproliferative properties, on ...
Aspirin attenuates morphine antinociceptive tolerance in rats with diabetic neuropathy by inhibiting apoptosis in the dorsal root ganglia
(2023)
Morphine is a drug used in chronic pain such as diabetic neuropathy, but the development of tolerance to its antinoci ceptive efect is an important clinical problem. Aspirin is an analgesic and antiapoptotic drug used in ...
Preventive effects of Capparis Spinose extract on experimental periodontitis in rats: a histopathological and biochemical study
(2023)
This study aimed to assess the effectiveness of Capparis Spinose (CS) in preventing the initiation and pro gression of experimental periodontitis and to evaluate the effect of its on systemic oxidative stress in rats by ...
Antimicrobially effective protein-loaded metal chelated chitosan composite
(1 Ağustos )
The immobilization of lysozyme onto a novel
synthetic metal chelator composite based on chitosan/
PAA-PMA (chitosan/acrylamide-maleic acid) and its effect
on antimicrobial activity were the aim of the current
study. ...
In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines
(MDPI, 28.09.2023)
We herein report the determination of the cytotoxic activity and expression profiles of
some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The
studied novel compounds were ...