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Metformin prevents morphine‑induced apoptosis in rats with diabetic neuropathy: a possible mechanism for attenuating morphine tolerance
(Springer, 2022)
Morphine is a drug of choice for the treatment of severe and chronic pain, but tolerance to the antinociceptive efect limits its use. The development of tolerance to morphine has recently been associated with neuronal ...
Aspirin attenuates morphine antinociceptive tolerance in rats with diabetic neuropathy by inhibiting apoptosis in the dorsal root ganglia
(2023)
Morphine is a drug used in chronic pain such as diabetic neuropathy, but the development of tolerance to its antinoci ceptive efect is an important clinical problem. Aspirin is an analgesic and antiapoptotic drug used in ...