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Molecular survey of Anaplasma phagocytophilum and related variants in water buffaloes: The first detection of Anaplasma phagocytophilum-like 1
(2023)
Anaplasma phagocytophilum infects various hosts and lead to mild to severe infection. Currently, two A.phagocytophilum-related variants have been documented in different countries. Although limited, there are studies ...
Kaempferol and Isorhamnetin alleviate Lipopolysaccharide-Induced Anxiety and Depression-Like Behavioral in Balb/C Mice
(09/07/2023)
The etiology of anxiety and depression is linked to inflammation and oxidative stress. Isorhamnetin
and Kaempferol are strong antioxidants with anti-inflammatory neuroprotective properties. This study, it was aimed to ...
Carvacrol Mitigates Bleomycin Induced Experimental Pulmonary Fibrosis
(23/08/2023)
Idiopathic pulmonary fibrosis (IPF) is a serious progressive pulmonary disease of
unknown etiology and high mortality. Carvacrol is a natural phenolic monoterpene with various
pharmacological effects, especially antioxidant ...
Lipid-lowering, antiinflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice
(05/2023)
Isorhamnetin is a hepatoprotective flavonoid molecule derived from the leaves and fruits of Hippophae rhamnoides L. However, the protective effect of isorhamnetin on acetaminophen (APAP) induced hepatotoxicity is still ...
The Effects of Sunitinib in Healthy and Cisplatin-Induced Rats
(04.01.2023)
Sunitinib is a multitargeted kinase inhibitor that inhibits many receptor tyrosine kinases and has been used in the treatment of gastrointestinal stromal tumors, metastatic renal cell carcinoma, and pancreatic neuroendocrine ...
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats
(20.02.2023)
Objectives Cyclophosphamide is a chemotherapeutic agent and immunosuppressant drug; however, it damages the liver. This study investigates the protective effect of ethanolic extract of Allium scorodoprasum (ASE) on ...
The effects of sorafenib in healthy and cisplatin-treated rats
(07.10.2023)
Background. Sorafenib is a multikinase inhibitor currently used in the treatment of hepatocellular carcinoma, renal cell carcinoma and thyroid cancer.
Objectives. The literature on this agent is scarce. This study aimed ...
FGF-18 alleviates memory impairments and neuropathological changes in a rat model of Alzheimer's disease
(22.07.2023)
Alzheimer’s disease (AD) is a multifactorial pathology marked by amyloid beta (Aβ) accumulation, tau hyperphosphorylation, and progressive cognitive decline. Previous studies show that fibroblast growth factor 18 (FGF18) ...
Mechanism of anticancer effect of gambogic acid on gastric signet ring cell carcinoma
(16.08.2023)
Gambogic acid has demonstrated inhibitory effects on the growth of various cancer cell types, such as breast cancer, pancreatic cancer, prostate cancer, lung cancer, and osteosarcoma. This study aims to investigate the ...